Israeli Judicious Antibiotic Prescription Study
IJAP
Can Change in Physicians' Prescribing Habits Decrease Carriage of Resistant Bacteria in the Community?
1 other identifier
interventional
5,700
0 countries
N/A
Brief Summary
This study aims to implement judicious antibiotic prescription habits to primary care pediatricians using a multifacet educational intervention and assess two main outcomes: 1) Direct outcome - prescription rates of the physicians. 2)Indirect outcome - carriage of antibiotic resistant bacteria by the treated population, specifically nasopharyngeal S. pneumoniae, nasal S. aureus and rectal E.coli.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Feb 2002
Longer than P75 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2002
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2005
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2007
CompletedFirst Submitted
Initial submission to the registry
August 23, 2010
CompletedFirst Posted
Study publicly available on registry
August 24, 2010
CompletedAugust 24, 2010
August 1, 2010
3.7 years
August 23, 2010
August 23, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
antibiotic prescription rate of physicians
Antibiotic prescrption rate at baseline will be compared to changes following the intervention between the 2 groups (control and intervention).
5 years
Secondary Outcomes (1)
Carriage of antibiotic resistant bacteria by treated patients
4 years
Study Arms (2)
Educational intervention
EXPERIMENTALMultifacet educational intervention that includes workshops, seminars and focus group meetings
Control - no intervention
NO INTERVENTIONThis group did not have any intervention, but their population was screened for carriage of antibiotic resistant bacteria
Interventions
Multifacet intervention that includes: Guideline preparation and implementation, preparing clinic campaign, improving knowledge about Ab resistance and diagnosis of respiratory infections
Eligibility Criteria
You may qualify if:
- All treated patients of the participating physicians under the age of 5y, who came for any reason for a visit during the study period, who's parents agreed to participate.
You may not qualify if:
- The only reason to exclude a child from being recruited was age\>5y or refusal of the parent/child to participate.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Sheba Medical Centerlead
- Maccabi Healthcare Services, Israelcollaborator
Related Publications (1)
Regev-Yochay G, Raz M, Dagan R, Roizin H, Morag B, Hetman S, Ringel S, Ben-Israel N, Varon M, Somekh E, Rubinstein E. Reduction in antibiotic use following a cluster randomized controlled multifaceted intervention: the Israeli judicious antibiotic prescription study. Clin Infect Dis. 2011 Jul 1;53(1):33-41. doi: 10.1093/cid/cir272.
PMID: 21653300DERIVED
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
Study Record Dates
First Submitted
August 23, 2010
First Posted
August 24, 2010
Study Start
February 1, 2002
Primary Completion
October 1, 2005
Study Completion
December 1, 2007
Last Updated
August 24, 2010
Record last verified: 2010-08