NCT06309069|Completed
Calcified Cerebral Embolism: a Descriptive Study in a Large Single Center Cohort
CCE Cohorte
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CCE Cohorte
Sponsor study identifier
Secondary identifiers
OTHER · IRB
observational
79
1 country
1
Study Start
April 16, 2024
Actual (reported)Primary Completion
November 30, 2024
Actual (reported)Study Completion
November 30, 2024
Actual (reported)Calcified cerebral embolism (CCE) is a relatively rare but underdiagnosed cause of infarction. CCE diagnosis is made by CT. Radiological characteristics of CCE have been reported in small case series. The aim of this study was to describe clinical and radiological characteristics of CCE in a large number of patients, and to compare patients with different radiological CCE characteristics.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 30, 2024
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 26, 2024
Actual (reported)March 13, 2024
Actual (reported)April 16, 2024
Actual (reported)November 30, 2024
Actual (reported)November 30, 2024
Actual (reported)Calcified aortic brachiocephalic
looking for calcified aortic brachiocephalic (presence or absence)
baseline
cardiovascular risk
Study of cardiovascular risk factors (presence or absence)
baseline
history of stroke
Presence of a history of stroke (y/n)
baseline
Population
demographic characteristics age (years)
baseline
Population
demographic characteristics sexe (M/F)
baseline
history of surgical/endovascular cardiovascular intervention
surgical/endovascular cardiovascular intervention (y/n)
CCE patients identified between 2015 and 2023
None, purely observational study
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Patients with CEE treated with intravenous thrombolysis (IVT) between 2015 and 2020, and patients with AIT/stroke with a CCE identified on CT between deceber 2019 and april 2023.
CHU de Nîmes
Nîmes, 30029, France
Serghine Y, Laurent-Chabalier S, Thouvenot E, Parvu T, Renard D. Clinical and radiological characteristics of calcified cerebral embolism: a large case series including 242 calcified cerebral embolism. Acta Neurol Belg. 2025 Apr;125(2):463-468. doi: 10.1007/s13760-025-02719-w. Epub 2025 Jan 15.
Anissa MEGZARI
Centre Hospitalier Universitaire de Nīmes
79 participants (actual enrollment reported by the registry).
First Submitted
February 26, 2024
First Posted
March 13, 2024
Study Start
April 16, 2024
Actual (reported)baseline
NIHSS
NIHSS score (Score between 1 and 4: minor stroke, Score between 5 and 15: moderate, stroke, Score between 15 and 20: severe stroke) Score \> 20: severe stroke
baseline
calcified aortic arch
looking for calcified aortic arch (presence/absence)
baseline
calcified carotid
looking for calcified carotid (presence/absence)
baseline
atherosclerotic plaques
looking for atherosclerotic plaques (presence/absence)
baseline
calcified aortic valves
looking for calcified aortic valves (presence/absence)
baseline
calcified mitral valves
looking for calcified mitral valves (presence/absence)
baseline
CCE diameter
CCE diameter measurement (mm)
baseline
density
CCE density (uh)
baseline
involved cerebral artery
description of involved cerebral artery
baseline
Contact the study team to confirm eligibility.
Primary Completion
November 30, 2024
Actual (reported)Study Completion
November 30, 2024
Actual (reported)Last Updated
January 23, 2026
Record last verified: 2025-12
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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