NCT06302075

Brief Summary

The study is defined as prospective, randomized, interventional single-center; the general aim is to evaluate the post-operative recovery of the patient who carries out rehabilitation with the one day protocol (Group A), compared to the patient who carries out rehabilitation during the hospital stay with the fast protocol (group B).

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2021

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 16, 2021

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

March 4, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 8, 2024

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2025

Completed
Last Updated

March 12, 2024

Status Verified

March 1, 2024

Enrollment Period

3.1 years

First QC Date

March 4, 2024

Last Update Submit

March 8, 2024

Conditions

Keywords

Gonarthrosisrehabilitation

Outcome Measures

Primary Outcomes (1)

  • Knee Society Score (KSS) from 0 to 100 (whether higher scores mean a better outcome)

    To evaluate the KSS at 1 month from the surgery

    1 month

Study Arms (2)

One Day Rehabilitation

EXPERIMENTAL

discharged home the day after the operation (24 hours) and carrying out outpatient rehabilitation according to the clinical standard

Other: One Day Rehabilitation

Fast Rehabilitation

ACTIVE COMPARATOR

discharged to the rehabilitation department of the Institute 48 hours after surgery which carries out rehabilitation during the hospital stay according to the clinical standard

Other: Fast Rehabilitation

Interventions

Patient discharged at home the day after the operation and carrying out outpatient rehabilitation according to the clinical standard

One Day Rehabilitation

Patient discharged to the rehabilitation department of the Institute 48 hours after surgery which carries out rehabilitation during the hospital stay according to the clinical standard

Fast Rehabilitation

Eligibility Criteria

Age40 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 40\<x\<85 included
  • Medial monocompartmental gonarthrosis grade 3-4 sec Kellgren-Lawrence
  • Primary medial gonarthrosis
  • Signing of the Informed Consent and consent to collaborate in all study procedures.

You may not qualify if:

  • Cognitive decline
  • Psychiatric disorders
  • Neuromuscular disorders
  • Age \> 85 years or \<40
  • Lateral gonarthrosis grade 3-4 sec Kellgren-Lawrence
  • Patella symptoms
  • Secondary medial gonarthrosis
  • Minor age
  • Pregnant women (self-declaration)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istituto Clinico San Siro

Milan, Italia, Italy

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

Rehabilitation

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Intervention Hierarchy (Ancestors)

AftercareContinuity of Patient CarePatient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 4, 2024

First Posted

March 8, 2024

Study Start

November 16, 2021

Primary Completion

December 31, 2024

Study Completion

December 1, 2025

Last Updated

March 12, 2024

Record last verified: 2024-03

Locations