NCT06300710

Brief Summary

  1. 1.To detect the frequency and the underlying causes of cardiopulmonary arrest .
  2. 2.To detect outcome of CPR
  3. 3.To identify the associated risk factors for the different outcomes after CPR among those patients

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Aug 2024

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 21, 2024

Completed
16 days until next milestone

First Posted

Study publicly available on registry

March 8, 2024

Completed
5 months until next milestone

Study Start

First participant enrolled

August 1, 2024

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2025

Completed
28 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2025

Completed
Last Updated

July 30, 2024

Status Verified

March 1, 2024

Enrollment Period

6 months

First QC Date

February 21, 2024

Last Update Submit

July 29, 2024

Conditions

Cardio Respiratory Arrest

Outcome Measures

Primary Outcomes (1)

  • incidence of cardiac arrest and survival to discharge from the PICU (dead versus alive)

    (dead versus alive)

    1 year

Secondary Outcomes (1)

  • Rate of risk factors associated with outcome of CPR

    1 year

Eligibility Criteria

Age1 Month - 18 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Children aged from 1 month to 18 years who suffered in-PICU CA between March 2024 to February 2025 will be included. Cardiopulmonary arrest was defined as the presence of unresponsiveness, apnea, absence of signs of life, and absence of a palpable central pulse or bradycardia of \<60 bpm with poor perfusion in infants, requiring external cardiac compressions and assisted ventilation

You may qualify if:

  • Including Children aged 1 month to 18 years who received at least 1 minute of CPR

You may not qualify if:

  • terminal disease patients, such as malignancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (5)

  • Lee EP, Chan OW, Lin JJ, Hsia SH, Wu HP. Risk Factors and Neurologic Outcomes Associated With Resuscitation in the Pediatric Intensive Care Unit. Front Pediatr. 2022 Apr 4;10:834746. doi: 10.3389/fped.2022.834746. eCollection 2022.

    PMID: 35444968BACKGROUND

  • Choi J, Choi AY, Park E, Moon S, Son MH, Cho J. Trends in Incidences and Survival Rates in Pediatric In-Hospital Cardiopulmonary Resuscitation: A Korean Population-Based Study. J Am Heart Assoc. 2023 Feb 7;12(3):e028171. doi: 10.1161/JAHA.122.028171. Epub 2023 Jan 25.

    PMID: 36695322BACKGROUND

  • Perkins GD, Jacobs IG, Nadkarni VM, Berg RA, Bhanji F, Biarent D, Bossaert LL, Brett SJ, Chamberlain D, de Caen AR, Deakin CD, Finn JC, Grasner JT, Hazinski MF, Iwami T, Koster RW, Lim SH, Huei-Ming Ma M, McNally BF, Morley PT, Morrison LJ, Monsieurs KG, Montgomery W, Nichol G, Okada K, Eng Hock Ong M, Travers AH, Nolan JP; Utstein Collaborators. Cardiac arrest and cardiopulmonary resuscitation outcome reports: update of the Utstein Resuscitation Registry Templates for Out-of-Hospital Cardiac Arrest: a statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia); and the American Heart Association Emergency Cardiovascular Care Committee and the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Circulation. 2015 Sep 29;132(13):1286-300. doi: 10.1161/CIR.0000000000000144. Epub 2014 Nov 11.

    PMID: 25391522BACKGROUND

  • Kuisma M, Suominen P, Korpela R. Paediatric out-of-hospital cardiac arrests--epidemiology and outcome. Resuscitation. 1995 Oct;30(2):141-50. doi: 10.1016/0300-9572(95)00888-z.

    PMID: 8560103BACKGROUND

  • Reis AG, Nadkarni V, Perondi MB, Grisi S, Berg RA. A prospective investigation into the epidemiology of in-hospital pediatric cardiopulmonary resuscitation using the international Utstein reporting style. Pediatrics. 2002 Feb;109(2):200-9. doi: 10.1542/peds.109.2.200.

    PMID: 11826196BACKGROUND

MeSH Terms

Conditions

Heart Arrest

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Central Study Contacts

Eman HK Khalaf, Resident physician

CONTACT

+201111452811emanh.khalaf1911@yahoo.com

Zeinab Mohamed Mohieldeen, Professor

CONTACT

01149913112zeinabmohieldeen1993@aun.edu.eg

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

February 21, 2024

First Posted

March 8, 2024

Study Start

August 1, 2024

Primary Completion

February 1, 2025

Study Completion

March 1, 2025

Last Updated

July 30, 2024

Record last verified: 2024-03