Comparison of Constraint Induced Movement Therapy and Mirror Therapy

NCT06294444 | Completed DMC

• 1 other identifier: REC/RCR&AHS/23/0741
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 2

Brief Summary

Hemiplegia in infants and children is a type of Cerebral Palsy that results from damage to the part (hemisphere) of the brain that controls muscle movements. This damage may occur before, during or shortly after birth. The term hemiplegia means that the paralysis is on one vertical half of the body. The aim of this study will be the to know the effect of mCIMT with and without mirror therapy on upper limb function in children with hemiplegic cerebral palsy. A randomized control trial will be conducted at Sheikh Zayed Hospital, RYK through convenience sampling technique on 30 patients which will be allocated through simple random sampling through sealed opaque enveloped into group A and group B. Group A will be treated with mCIMT and Group B will be treated with mCIMT and mirror therapy. Outcome measure will be conducted through pain and disability questionnaire after 6 weeks. Data will be analyzed using SPSS software version 21. After assessing normality of data by Shapiro - wilk test, it will be decided either parametric or non-parametric test will be used within a group or between two groups. mCIMT with and without mirror therapy will be applied in patients with hemiplegic cerebral palsy to see the effect on upper limb function.

Conditions

Hemiplegic Cerebral Palsy

Keywords

mCIMT, Hemiplegia, Mirror therapy

Outcome Measures

Primary Outcomes (1)

• fine motor skills

  The Melbourne Assessment 2 (MA2): a test of quality of unilateral upper limb function. Is a criterion-referenced test for children aged 2.5 to 15 years with neurological impairments providing measurement of four elements of upper limb movement quality: range of movement, accuracy, dexterity and fluency. FHGT: The subject holds the dynamometer in the hand to be tested, with the arm at right angles and the elbow by the side of the body. The handle of the dynamometer is adjusted if required - the base should rest on the first metacarpal (heel of palm), while the handle should rest on middle of the four fingers. When ready the subject squeezes the dynamometer with maximum isometric effort, which is maintained for about 5 seconds. No other body movement is allowed. The subject should be strongly encouraged to give a maximum effort. MMT: Manual Muscle Testing Grades 0-5

  6weeks

Study Arms (2)

Constraint induced Movement Therapy

EXPERIMENTAL

Group of 15 members will be given constraint induced movement therapy for 6 weeks.

Other: Constraint Induced Movement Therapy

Mirror therapy group

EXPERIMENTAL

Group of 15 members will be given modified constraint induced movement therapy with mirror theray for 6 weeks.

Other: Mirror therapy

Interventions

Constraint Induced Movement Therapy OTHER

Group A: This group patients will be treated with mCIMT, the forced use of the affected arm by restraining the unaffected arm, with a sling or a hand splint, during dedicated exercise sections or usual ADLs (90% of waking hours).Massed practice (eight hours of exercise) of the affected arm through a shaping method, where shaping involves a commonly operant conditioning method in which a behavioural objective (in this case 'movement') is approached in small steps of progressively increasing difficulty. The participant is rewarded with enthusiastic approval for improvement, but never blamed or punished for failure. This therapy will be given 4hrs daily for 6 weeks. The results will be based upon pre and post evaluation.

Also known as: Mirror Therapy

Constraint induced Movement Therapy

Mirror therapy OTHER

Group B: These patients will be treated with mCIMT and mirror therapy. Children were taught repetitive symmetrical upper limbs exercises: with modelling-clay in each hand to elicit bilateral thumb-finger pinch and grasping. They performed these during a 15-minute daily routine at home with mCIMT (forced use of arm and massed practice 4hrs of exercise of affected arm). This combination of therapy will be given for 6 weeks. The results will be seen through pre and post evaluation.

Mirror therapy group

Eligibility Criteria

• Age: 6 Years - 12 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Medically diagnosed with Hemiplegic CP
• Age ranges btween3-12 years
• Hemiplegic CP with motor disability
• No major contractures of upper limb muscle
• Both genders were included
• Able to follow command
• No orthopedic surgery during the previous six months(8)

You may not qualify if:

• Functional limb
• Patients with contracture
• Patient with sensory,cognitive and perceptual disorders
• Patient with seizures
• Patient with orthopedic surgery

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (2)

Imran Amjad

Lahore, Punjab Province, 54000, Pakistan

Location

Riphah International University

Lahore, Punjab Province, Pakistan

Location

Related Publications (1)

• Oliva-Sierra M, Rios-Leon M, Abuin-Porras V, Martin-Casas P. [Effectiveness of mirror therapy and action observation therapy in infantile cerebral palsy: a systematic review]. An Sist Sanit Navar. 2022 Aug 16;45(2):e1003. doi: 10.23938/ASSN.1003. Spanish.

  PMID: 35972309 BACKGROUND

MeSH Terms

Conditions

Hemiplegia

Interventions

Constraint Induced Movement Therapy; Mirror Movement Therapy

Condition Hierarchy (Ancestors)

Paralysis; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Exercise Therapy; Physical Therapy Modalities; Therapeutics; Rehabilitation

Study Officials

• Hurriya Sehar, MS*

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Participants will get separate treatment protocol and possible efforts will be put to mask the both groups about their treatment
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomized Control Trial

Study Record Dates

• First Submitted: December 26, 2023
• First Posted: March 5, 2024
• Study Start: December 1, 2023
• Primary Completion: March 15, 2024
• Study Completion: March 15, 2024
• Last Updated: May 7, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

PA (2)