Clinical Characteristics and Surgical Outcomes of the Fellow Eye in Bilateral Retinal Detachments

NCT06292572 | Not Yet Recruiting

• 1 other identifier: 2024PI029
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

To assess the clinical features and the surgical outcomes of RD repair surgery of the fellow eye in bilateral retinal detachments

Conditions

Retinal Detachment

Keywords

retinal detachment; bilateral; vitrectomy

Outcome Measures

Primary Outcomes (1)

• Rate of surgical success

  Rate of succesful surgical repair of RD within the follow-up period

  6 month after surgery

Secondary Outcomes (1)

• Visual Acuity

  6 month after surgery

Study Arms (2)

Initial Retinal Detachment

First of both eyes of the same patient that underwent retinal detachment repair

Procedure: Retinal Detachment Surgery

Subsequent Retinal Detachment

Subsequent eye undergoing retinal detachment repair

Procedure: Retinal Detachment Surgery

Interventions

Retinal Detachment Surgery PROCEDURE

Retinal Detachment Surgery that consists in either Pars Plana Vitrectomy or Scleral Buckling or a combination of both techniques, and with or without use of intraocular tamponade

Also known as: Pars plana Vitrectomy (PPV), Scleral Buckle (SB), PPV + SB

Initial Retinal Detachment; Subsequent Retinal Detachment

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients that underwent retinal detachment repair surgery for bilateral sequentiel retinal detachment between January 2016 and December 2023 at the Nancy Regional and University Hospital Center

You may qualify if:

• All patients that underwent retinal detachment repair surgery for bilateral sequential retinal detachment between January 2016 and December 2023 at the Nancy Regional and University Hospital Center (via pars plana vitrectomy or scleral buckling) and with a minimum of 6 month of post-operative follow-up after the last surgery.

You may not qualify if:

• Patients that underwent surgery at another facility
• Patients with a history of previous vitrectomy or
• Patients with a history of trauma from a penetrating injury or ruptured globe, retinal neovascular condition, hereditary vitreo-retinopathy

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Study Sites (1)

CHRU de Nancy

Vandœuvre-lès-Nancy, Meurthe-et-Moselle, 54511, France

Location

Related Publications (5)

• Xu D, Belin PJ, Staropoli PC, Yannuzzi NA, Vangipuram G, Chiang A, Shah GK, Townsend JH, Ryan EH, Klufas MA. Clinical Outcomes in Sequential, Bilateral Rhegmatogenous Retinal Detachment: A Multicenter, Paired-Eye Analysis. Ophthalmol Retina. 2021 Aug;5(8):797-804. doi: 10.1016/j.oret.2020.11.002. Epub 2020 Nov 14.

  PMID: 33197679 BACKGROUND

• Walia HS, Shah GK, Blinder KJ. Characteristics and outcomes of sequential rhegmatogenous retinal detachments. Ophthalmic Surg Lasers Imaging Retina. 2015 Apr;46(4):445-9. doi: 10.3928/23258160-20150422-07.

  PMID: 25970865 BACKGROUND

• Mitry D, Singh J, Yorston D, Siddiqui MA, Murphy AL, Wright AF, Fleck BW, Campbell H, Charteris DG. The fellow eye in retinal detachment: findings from the Scottish Retinal Detachment Study. Br J Ophthalmol. 2012 Jan;96(1):110-3. doi: 10.1136/bjo.2010.194852. Epub 2011 Mar 3.

  PMID: 21378003 BACKGROUND

• Radeck V, Schindler F, Helbig H, Gamulescu MA, Cvetkov Y, Barth T, Maerker D. Characteristics of Bilateral Retinal Detachment. Ophthalmologica. 2023;246(2):99-106. doi: 10.1159/000527625. Epub 2022 Oct 25.

  PMID: 36282053 BACKGROUND

• Mastropasqua L, Carpineto P, Ciancaglini M, Falconio G, Gallenga PE. Treatment of retinal tears and lattice degenerations in fellow eyes in high risk patients suffering retinal detachment: a prospective study. Br J Ophthalmol. 1999 Sep;83(9):1046-9. doi: 10.1136/bjo.83.9.1046.

  PMID: 10460773 BACKGROUND

MeSH Terms

Conditions

Retinal Detachment

Interventions

Scleral Buckling; Predictive Value of Tests

Condition Hierarchy (Ancestors)

Retinal Diseases; Eye Diseases

Intervention Hierarchy (Ancestors)

Ophthalmologic Surgical Procedures; Surgical Procedures, Operative; Sensitivity and Specificity; Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Jean-Baptiste Conart, MD, PhD

  CHRU de Nancy

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ida Gordon

CONTACT

+33622820203; gordon.ida14@gmail.com

Jean-Baptiste Conart, MD, PhD

CONTACT

jbconart@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, PhD

Study Record Dates

• First Submitted: February 27, 2024
• First Posted: March 5, 2024
• Study Start: March 1, 2024
• Primary Completion: November 1, 2024
• Study Completion: November 1, 2024
• Last Updated: March 5, 2024

Record last verified: 2024-02

Locations

FR (1)