Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication

NCT06291389 | Recruiting

• 1 other identifier: RC.2.8.2023
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

An abdominal panniculus excision procedure is known as an abdominoplasty (panniculectomy). Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti muscles. This study aimed to evaluate the effect of intraoperative changes in peak airway pressure (PAP) after muscle plication on postoperative pulmonary function.

Conditions

Abdominal Compartment Syndrome

Outcome Measures

Primary Outcomes (1)

• Intraoperative peak airway pressure (PAP)

  Intraoperative peak airway pressure (PAP) will be observed Pre-plication, Post- plication in supine position and Post- plication in semi-sitting position

  4 hours

Secondary Outcomes (4)

• Duration of oxygen therapy

  1 week

• Post operative Tidal Volume (Vt) (Measured by spirometer)

  24 hours postoperatively

• Post operative Respiratory Rate (RR)

  24 hours postoperatively

• Hospital stay.

  1 week

Eligibility Criteria

• Age: 20 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

age ranged between 20 and 50 years old,- American Society of Anesthesiologists (ASA) physical status classification I and came for abdominoplasty operation

You may qualify if:

• age ranged between 20 and 50 years old,
• American Society of Anesthesiologists (ASA) physical status classification I
• came for abdominoplasty operation

You may not qualify if:

• anemia or hemoglobin levels below 11g/dl
• bleeding problems
• cardiovascular disorders
• restrictive and obstructive respiratory disease
• abdominoplasty without plication.

Sponsors & Collaborators

• Al-Azhar University: lead
• Benha University: collaborator

Study Sites (1)

Neveen Kohaf

Tanta, Egypt, 11865, Egypt

RECRUITING

MeSH Terms

Conditions

Intra-Abdominal Hypertension

Condition Hierarchy (Ancestors)

Compartment Syndromes; Muscular Diseases; Musculoskeletal Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Neveen Kohaf, ph.d

  Al-Azhar University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Neveen Kohaf, Ph.D

CONTACT

+201060383012; nevenabdo@azhar.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Clinical Pharmacy

Study Record Dates

• First Submitted: February 26, 2024
• First Posted: March 4, 2024
• Study Start: March 10, 2024
• Primary Completion (Estimated): December 15, 2026
• Study Completion (Estimated): December 15, 2026
• Last Updated: January 6, 2026

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP

Locations

EG (1)