Validation of the Girls Questionnaire for Autism Spectrum Condition in French Langage

NCT06280521 | Not Yet Recruiting

• 1 other identifier: 38RC23.0331
• Study Type: interventional
• Target: 400
• Locations: 0 countries
• Sites: N/A

Brief Summary

Autism spectrum disorders (ASD) are currently diagnosed at a rate of approximately 3 males per 1 female, while evidence suggests the rate may be 1.8 males per 1.2 females. It has been shown that affected women receive an autism diagnosis on average 5 years later than men. This delay is associated with deleterious consequences on the educational, psychological and physical health levels in these women. Currently, there are a number of obstacles that delay or prevent women with ASD from accessing diagnosis and specialized support. These include, in particular, gendered assumptions about how ASD manifests depending on the gender of the person concerned, a tendency for clinicians to attribute female autistic traits to causes other than ASD, measures of standardized ASD assessments that may not be sensitive enough to identify ASD females, and finally a demonstrated greater tendency among ASD females to camouflage or mask autistic traits in order to blend in in social situations. It is in this context that the Girl Questionnaire for Autism Spectrum Conditions (GQ-ASC) was developped and validated to address these fundamental gaps in the early identification and measurement of female ASD symptoms. The GQ-ASC is presented as a self-questionnaire with 29 items which assess clinical characteristics specific to the adult female presentation of ASD in the dimensions (five) of imagination and play, camouflage, sensoriality, social situations and interests. To date, several studies have relevantly used the GQ-ASC in populations of adult ASD women, but none in French. The main objective of this online study is therefore to measure the predictive validity of the French version of the Girl Questionnaire for Autism Spectrum Conditions (fGQ-ASC) for the diagnosis of ASD in adult women over 18 years of age and speaking French kindergarten. Subjects included in this online study will complete the protocol using any computer, tablet, or cell phone. We will include 400 participants (100 females-ASD, 100 females-nonASD, 100 males-ASD, 100 males-nonASD). This study will validate for the first time a screening tool for the diagnosis of ASD in women of French mother tongue over 18 years of age (the Girls Questionnaire for Autism Spectrum Condition French version - fGQ-ASC). This tool will have particularly significant benefits since it will help reduce the diagnostic delay among adult women with ASD in France and accelerate their access to specialized support.

Conditions

Autism Spectrum Disorder

Outcome Measures

Primary Outcomes (1)

• VP fGQ-ASC

  The main objective of this study is to measure the predictive validity of the French version of the Girl Questionnaire for Autism Spectrum Conditions (fGQ-ASC) for the diagnosis of ASD in adult women over 18 years old and of French mother tongue.

  baseline

Study Arms (4)

Women with autistic spectrum disorder

OTHER

Other: fGQ-ASC

Men with autistic spectrum disorder

OTHER

Other: fGQ-ASC

Women without autistic spectrum disorder

OTHER

Other: fGQ-ASC

Men without autistic spectrum disorder

OTHER

Other: fGQ-ASC

Interventions

fGQ-ASC OTHER

French version of the Girl Questionnaire for Autism Spectrum Conditions (fGQ-ASC)

Men with autistic spectrum disorder; Men without autistic spectrum disorder; Women with autistic spectrum disorder; Women without autistic spectrum disorder

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: 50/50
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• All groups: 18 years or older, French mother tongue
• ASD groups: have a diagnosis of ASD without intellectual development disorder (intellectual disability) made by professionals trained in autism

Sponsors & Collaborators

• University Hospital, Grenoble: lead

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 5, 2024
• First Posted: February 28, 2024
• Study Start: April 1, 2024
• Primary Completion: April 1, 2026
• Study Completion: May 1, 2026
• Last Updated: February 28, 2024

Record last verified: 2024-02