NCT06269029

Brief Summary

Chest mobility exercise versus proprioceptive neuromuscular facilitation in patients with chronic obstructive pulmonary disease

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 17, 2024

Completed
1 month until next milestone

Study Start

First participant enrolled

February 17, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 21, 2024

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2024

Completed
Last Updated

July 22, 2024

Status Verified

July 1, 2024

Enrollment Period

4 months

First QC Date

January 17, 2024

Last Update Submit

July 18, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pulmonary function test

    Spirometry is the most common pulmonary function test. It is widely used in the assessment of lung function to provide objective information used in the diagnosis of lung diseases and monitoring lung health Test started at the time of 20 minutes after subjects inhaling 400 μg of salbutamol. The following variables were assessed: FVC, FEV1, inspiratory capacity (IC), and inspiratory reserve volume (IRV)

    One week for each comparator

Study Arms (2)

patients with COPD assigned for chest mobility

EXPERIMENTAL

This study will be carried on 30 patients with Chronic obstructivepulmonarydisease. Patients will be selected from department (3) Kaser EL-Ainy, Cairo University.

Other: Chest mobility exercises

patients with COPD assigned for PNF

EXPERIMENTAL

This study will be carried on 30 patients with Chronicobstructivepulmonarydisease. Patients will be selected from department (3) Kaser EL-Ainy, Cairo University.

Other: proprioceptive neuromuscular facilitation

Interventions

exercises were repeated 6 times on each side with rest of period for 30 seconds in between. The intervention will be carried out for one week with total of 7 sessions. Each Exercise will be accompanied by breathing pattern. In neutral position of exercises, subjects will be asked to exhale during flexion, turning or extension subject will be asked to do inhale.

patients with COPD assigned for chest mobility

The technique used in this study Proprioceptive neuromuscular facilitation technique of hold and relax stretching for isolated clavicular head of the pectoralis major muscle. The subjects sitting on a chair with back support to keep spine in a neutral position and both their arms are extended and hands are placed behind the occipital region. His both arms will be positioned in glenohumeral horizontal extension, and glenohumeral abduction and external rotation with elbow bent to perform stretch position of pectoral muscle. Then ask him to contract the pectoral muscles .This isometric contraction is held for 6 seconds. The patient then relaxed and passive stretch in the opposite direction . and it was repeated 6 times with rest period 30 seconds. The session will be given every day for one week

patients with COPD assigned for PNF

Eligibility Criteria

Age50 Years - 60 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • All patients will have the following criteria:
  • Age: 50-60 years old
  • All patients will be in mild to moderate of COPD. In accordance with criteria of Global Initiative for Chronic Obstructive Lung Disease (GOLD) (GOLD I-II).
  • BMI: obese class 1 (30-34.9).
  • Sex: male
  • They suffered from mild dyspnea, chronic cough and expectorations, with forced expiratory volume in one second (FEV1sec) from 50% to 80% of predicted value.

You may not qualify if:

  • Patients with the following criteria will excluded from the study:
  • Severe psychiatric or cognitive impairments.
  • Progressive neuromuscular disorders.
  • Decreased level of consciousness.
  • Unstable fracture.
  • pacemaker inserted for fewer than 2 days
  • Deep-venous thrombosis (to minimize risk for pulmonary embolism from being in a prone position.
  • Mean arterial blood pressure of less than 65 mm Hg with or without vasopressors.
  • Tracheal surgery or sternotomy in the last 15 days.
  • Massive haemoptysis.
  • Intracranial pressure of more than 30 mm Hg or cerebral perfusion pressure of less than 60 mm Hg.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cairo university- faculty of physical therapy

Cairo, Dokki, 12556, Egypt

Location

Related Publications (1)

  • Zakaria I, Serry ZMH, Soliman YMA, Aziz MM, Mohamed MI, Guirguis SA. Chest mobility exercises versus proprioceptive neuromuscular facilitation in patients with chronic obstructive pulmonary disease: A randomized trial. J Bodyw Mov Ther. 2025 Oct;44:400-408. doi: 10.1016/j.jbmt.2025.05.057. Epub 2025 Jun 4.

MeSH Terms

Interventions

Muscle Stretching Exercises

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Zahra Serry

    Faculty of physical therapy- internal medicine department

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

January 17, 2024

First Posted

February 21, 2024

Study Start

February 17, 2024

Primary Completion

June 30, 2024

Study Completion

June 30, 2024

Last Updated

July 22, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share

Locations