The Impact of Parasitic Infection on Multiple Sclerosis and Nephrotic Syndrome

NCT06256471 | Not Yet Recruiting

• 1 other identifier: Parasitic infection
• Study Type: observational
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

1. 1.Detection of the prevalence of parasitic infections amoung patients with multiple sclerosis and nephrotic syndrome at Assiut University Hospitals.
2. 2.Detection of the effect of parasitic infections on these diseases courses.
3. 3.Inform authorities about the importance of management of parasitic infections in those patients.

Conditions

Parasitic Disease

Outcome Measures

Primary Outcomes (1)

• The impact of parasitic infection on multiple sclerosis and nephrotic syndrome

  Detection of prevalence of parasitic infection on multiple sclerosis and nephrotic syndrome and the effect of parasitic infection on these diseases courses

  Baseline

Interventions

Follow up of multiple sclerotic and nephrotic syndrome patients after 3 months OTHER

Follow up of multiple sclerotic and nephrotic syndrome patients after 3 months for detection of impact of parasitic infection on these diseases courses

Eligibility Criteria

• Age: Up to 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

clinically and laboratory-confirmed autoimmune diseases according to: multiple sclerosis attending Neurology Department at Assiut University Hospitals and clinically and laboratory-confirmed autoimmune diseases according to: nephrotic syndrome attending Pediatric Department at Assiut University Hospitals.

You may qualify if:

• \- 1- clinically and laboratory-confirmed autoimmune diseases according to: multiple sclerosis attending Neurology Department at Assiut University Hospitals.
• clinically and laboratory-confirmed autoimmune diseases according to: nephrotic syndrome attending Pediatric Department at Assiut University Hospitals.

You may not qualify if:

• Patients with other commodities especially which cause secondary immune deficiencies like diabetes mellitus, patients with chronic liver disease or kidney diseases other than NS, malignancies and pregnant females.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (2)

• Strachan DP. Hay fever, hygiene, and household size. BMJ. 1989 Nov 18;299(6710):1259-60. doi: 10.1136/bmj.299.6710.1259. No abstract available.

  PMID: 2513902 BACKGROUND

• Correale J, Farez M. Association between parasite infection and immune responses in multiple sclerosis. Ann Neurol. 2007 Feb;61(2):97-108. doi: 10.1002/ana.21067.

  PMID: 17230481 BACKGROUND

MeSH Terms

Conditions

Parasitic Diseases

Condition Hierarchy (Ancestors)

Infections

Central Study Contacts

Monica Refaat, Demonstrator

CONTACT

01093466250; Monicarefaat24@gmail.com

Magda Mohamed, Professor Doctor

CONTACT

01143533100; Magda.elnazer@med.aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Demonstrator

Study Record Dates

• First Submitted: February 5, 2024
• First Posted: February 13, 2024
• Study Start: June 1, 2024
• Primary Completion: June 1, 2025
• Study Completion: August 1, 2025
• Last Updated: February 13, 2024

Record last verified: 2024-02