NCT04314999

Brief Summary

The goal of this study is to describe the prevalence and the type of parasite in patients with a chronic spontaneous urticaria as well as to describe the associations between parasitic disease and the characteristics of the patients, for example eosinophilia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
57

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2019

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2019

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

March 12, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 19, 2020

Completed
Last Updated

March 19, 2020

Status Verified

March 1, 2020

Enrollment Period

4 months

First QC Date

March 12, 2020

Last Update Submit

March 16, 2020

Conditions

Keywords

Chronic Spontaneous UrticariaParasitic disease

Outcome Measures

Primary Outcomes (2)

  • Number of patients with parasite infestation

    assess number of patients with chronic spontaneous urticaria that have a parasite infestation (Analysis of stool samples by the Swiss Tropical and Public Health Institute (TPH), Basel)

    Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019

  • Most common parasite subgroup

    subtype determination from stool samples was performed by the Swiss TPH, Basel by polymerase chain reaction (PCR)

    Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019

Secondary Outcomes (2)

  • Correlation between migration Background/ travel history of the patients and parasite infestation

    Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019

  • Correlation between gastrointestinal complaints of the patients and parasite infestation

    Patients with a chronic spontaneous urticaria that were treated at the University hospital basel between the 1st of June 2019 and the 30th of September 2019

Study Arms (1)

Patients diagnosed with a chronic spontaneous urticaria

Patients with a chronic spontaneous urticaria who were being treated at the allergology of the university hospital Basel between the 1st of June and the 30th of September

Diagnostic Test: Examination of stool samples

Interventions

Tests for diagnosis of parasitic diseases

Patients diagnosed with a chronic spontaneous urticaria

Eligibility Criteria

Age17 Years+
Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with a chric spontaneous urticaria who were being treated at the allergology of the university hospital Basel between the 1st of June and the 30th of September.

You may qualify if:

  • Diagnosis of a chronic spontaneous urticaria
  • Age: 17 years old and up

You may not qualify if:

  • No diagnosis of a chronic spontaneous urticaria
  • Age: younger than 17 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Basel

Basel, 4031, Switzerland

Location

MeSH Terms

Conditions

Chronic UrticariaParasitic Diseases

Condition Hierarchy (Ancestors)

UrticariaSkin Diseases, VascularSkin DiseasesSkin and Connective Tissue DiseasesHypersensitivity, ImmediateHypersensitivityImmune System DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsInfections

Study Officials

  • Esther Steveling-Klein, Dr. med.

    Allergology, University Hospital Basel

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 12, 2020

First Posted

March 19, 2020

Study Start

June 1, 2019

Primary Completion

September 30, 2019

Study Completion

September 30, 2019

Last Updated

March 19, 2020

Record last verified: 2020-03

Locations