Study of the Dynamics of Verbal and Non-verbal Interaction in Healthy Subjects, Through the Recording of Body Movements and Non-invasive Neurophysiological Techniques

NCT06251479 | Recruiting

• 1 other identifier: OMNIBUS2023
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Based on study literature, the investigators can say that our study aims to give an explanation not only from a behavioral point of view but also with respect to what are the neuronal mechanisms underlying our ability to perceive and analyze our own and others' actions. This is essential to fully understand the complexity of our social behaviors. The knowledge of these mechanisms has a high value and relevant implications for many research fields both within and outside the neurosciences. The project aims to study the neurobehavioral correlates of verbal and non-verbal communication. Through the use of non-invasive behavioral and neurophysiological techniques, the study intends to highlight the neurobehavioral markers that allow to quantify the temporal evolution of communication dynamics in healthy subjects.

Conditions

Neuroscience; Neuromodulation

Outcome Measures

Primary Outcomes (1)

• Embodiment Scale

  patients have to experience rubber hand illusion first with a silicon and and second with a robotic hand. the embodiment variance is evaluted in the two condition with the embofiment scale

  1 hour

Secondary Outcomes (1)

• Embodiment Scale

  1 hour

Study Arms (4)

A group behavioral 1

EXPERIMENTAL

The first group will perform perceptual and verbal and non-verbal motor execution tasks, while behavioral measurement techniques will be used.

Behavioral: behavioral 1

B group behavioral 2

EXPERIMENTAL

The second group will perform the same tasks as group A and will be subjected to the same measurements as group A. Differently from group A, the members of group B will perform the experimental tasks together with another participant.

Behavioral: behavioral 2

C group neuromoulation 1

EXPERIMENTAL

The third group is identical to group A except that neurophysiological measurement techniques will also be applied.

Device: neuromodulation 1

D group neuromodulation 2

EXPERIMENTAL

The fourth group is identical to group B except that neurophysiological measurement techniques will also be applied.

Device: neuromodulation 2

Interventions

behavioral 1 BEHAVIORAL

verbal and non verbal tasks

A group behavioral 1

behavioral 2 BEHAVIORAL

verbal and non verbal tasks with other partecipants

B group behavioral 2

neuromodulation 1 DEVICE

registration with neurophysiological tecniques during verbal and non verbal tasks

C group neuromoulation 1

neuromodulation 2 DEVICE

registration with neurophysiological tecniques during verbal and non verbal tasks with other partecipants

D group neuromodulation 2

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age range between 18 and 55 years
• written informed consent
• healthy subjects

You may not qualify if:

• epilepsy or at risk of epileptic seizures,
• cardiac pacemaker wearers,
• presence of an implanted infusion pump,
• metal plaques in the skull or metal objects in the eye and skull taking neuroleptic drugs or tricyclic antidepressants,
• migraine or at risk of developing this disease.

Sponsors & Collaborators

• IRCCS Centro Neurolesi Bonino Pulejo: lead

Study Sites (1)

IRCCS Centro Neurolesi Bonino Pulejo

Messina, Messina, 98124, Italy

RECRUITING

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Caterina Formica, PhD, PSY

Study Record Dates

• First Submitted: December 28, 2023
• First Posted: February 9, 2024
• Study Start: August 16, 2023
• Primary Completion: December 28, 2023
• Study Completion (Estimated): August 16, 2026
• Last Updated: March 31, 2026

Record last verified: 2026-03

Locations

IT (1)