NCT06244563

Brief Summary

The purpose of this study is to assess and compare the effect of two appliances (Hybrid-Hyrax expander/ Bonded rapid maxillary expander (RME)) supported by different anchorage units and two different expansion procedures (routine rapid maxillary expansion protocol (routine)/ alternative rapid expansion and constriction protocol (alt-RAMEC)) on maxillary protraction during face mask (FM) treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 8, 2022

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 10, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 9, 2023

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

January 10, 2024

Completed
27 days until next milestone

First Posted

Study publicly available on registry

February 6, 2024

Completed
Last Updated

February 6, 2024

Status Verified

February 1, 2024

Enrollment Period

10 months

First QC Date

January 10, 2024

Last Update Submit

February 2, 2024

Conditions

Keywords

facemask treatment

Outcome Measures

Primary Outcomes (1)

  • Evaluation of Skeletal and Dental Changes in Millimetric Measurements

    Skeletal and dental changes in the maxilla and mandible were evaluated in millimetres using lateral radiographs taken before and after treatment. To determine skeletal changes A-VRP (mm), Co-A (mm), A-HRP (mm), Pog-VRP (mm), Co-Gn (mm) and WITS (mm) values were measured. To determine dental changes U1-VRP(mm), U1-HRP(mm), U6-VRP(mm), U6-HRP(mm), and L1-VRP(mm) values were measured.

    9 month

Secondary Outcomes (1)

  • Evaluation of Skeletal and Dental Changes in Angular Measurements

    9 month

Study Arms (4)

Face mask with Hybrid-Hyrax and Alt-RAMEC procedure

EXPERIMENTAL

The experimental group was comprised of 15 patients submitted to the alternate rapid maxillary expansion and constriction (alt-RAMEC) procedure for expansion protocol with a hybrid-hyrax expander as anchorage in the maxillary arch. The Face mask was used.

Device: Face mask with Hybrid-HyraxProcedure: Alternative Rapid Maxillary Expansion and Contraction Protocol (Alt-RAMEC)

Face mask with Bonded RME and Alt-RAMEC procedure

EXPERIMENTAL

The experimental group was comprised of 15 patients submitted to the alt-RAMEC procedure for expansion protocol with a bonded RME as anchorage in the maxillary arch. The Face mask was used.

Device: Face mask with Bonded RMEProcedure: Alternative Rapid Maxillary Expansion and Contraction Protocol (Alt-RAMEC)

Face mask with Hybrid-Hyrax and routine protocol

EXPERIMENTAL

The experimental group was comprised of 15 patients submitted to routine palatal expansion procedure (routine) with a hybrid-hyrax expander as anchorage in the maxillary arch. The Face mask was used.

Device: Face mask with Hybrid-HyraxProcedure: Routine Rapid Maxillary Expansion Protocol

Face mask with Bonded RME and routine protocol

ACTIVE COMPARATOR

The active comparator group was comprised of 15 patients who submitted to the routine expansion procedure with a bonded RME as anchorage in the maxillary arch. The Face mask was used.

Device: Face mask with Bonded RMEProcedure: Routine Rapid Maxillary Expansion Protocol

Interventions

Participants were treated with face mask using a Hybrid-Hyrax appliance as an anchor in the maxillary arch. The anchorage of hybrid-hyrax appliance was provided by bands adapted to the maxillary first permanent molars and two mini screws in the anterior palate. Force transmission was achieved using intermaxillary elastics that were connected to the face mask arms from the hooks of the hybrid-hyrax appliance in the maxillary canine region.

Face mask with Hybrid-Hyrax and Alt-RAMEC procedureFace mask with Hybrid-Hyrax and routine protocol

Participants were treated with face mask using a bonded RME appliance as an anchor in the maxillary arch. The anchorage of bonded RME appliance was provided by maxillary posterior teeth covered with acrylic cap. Force transmission was achieved using intermaxillary elastics that were connected to the face mask arms from the hooks of the bonded RME in the maxillary canine region.

Face mask with Bonded RME and Alt-RAMEC procedureFace mask with Bonded RME and routine protocol

In the groups that started with the Alt-Ramec protocol, the parents expanded the appliance screw twice a day in the first week and closed it in the opposite direction in the following week. This process was continued for 7-9 weeks according to the patient's need for expansion.

Face mask with Bonded RME and Alt-RAMEC procedureFace mask with Hybrid-Hyrax and Alt-RAMEC procedure

In the groups that started with the routine protocol, parents activated the expansion screw twice a day for 1-2 weeks, depending on the patient's need for expansion.

Face mask with Bonded RME and routine protocolFace mask with Hybrid-Hyrax and routine protocol

Eligibility Criteria

Age8 Years - 12 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Skeletal class III
  • Prepubertal growth stage
  • Reverse overjet

You may not qualify if:

  • Previous orthodontic treatment history
  • Patients with craniofacial abnormalities and syndromes.
  • Systemic diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gaziantep University

Gaziantep, Sehitkamil, 27310, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Malocclusion, Angle Class III

Interventions

Masks

Condition Hierarchy (Ancestors)

MalocclusionTooth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

Surgical AttireEquipment and Supplies, HospitalEquipment and SuppliesProtective DevicesPersonal Protective EquipmentSurgical EquipmentManufactured MaterialsTechnology, Industry, and Agriculture

Study Officials

  • Aysegul Gulec, PhD

    University of Gaziantep

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 10, 2024

First Posted

February 6, 2024

Study Start

June 8, 2022

Primary Completion

April 10, 2023

Study Completion

June 9, 2023

Last Updated

February 6, 2024

Record last verified: 2024-02

Data Sharing

IPD Sharing
Will not share

Locations