Effects of Aerobic Exercise and Core Muscle Strengthening on Pain, Menstrual Pattern and QOL in Endometriosis

NCT06241040 | Completed

• 1 other identifier: S22C14G92019
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Endometriosis is a complex and debilitating gynecological condition affecting millions of women worldwide. It is characterized by the abnormal growth of endometrial-like tissue outside the uterus, leading to chronic pelvic pain, dysmenorrhea, dyspareunia, and reduced quality of life. While pharmacological interventions are commonly prescribed to manage symptoms, their efficacy may be limited, and they often come with adverse effects. Therefore, exploring non-pharmacological approaches, such as exercise, is crucial in improving the management of endometriosis-related symptoms. Aerobic exercise has gained attention as a potential therapeutic intervention for endometriosis due to its positive effects on pain modulation, hormonal regulation, and overall well-being.

Conditions

Endometriosis

Keywords

Endometriosis; Menstrual pattern; Aerobic Exercise; Core Muscle Strengthening; Quality of Life

Outcome Measures

Primary Outcomes (3)

• Visual Analog Scale for Pain:

  The Visual Analog Scale (VAS) for Pain is a commonly used instrument for assessing pain intensity. It is a subjective measure that asks individuals to rate their pain on a continuous line or scale. The VAS typically consists of a 10 cm line with anchor points representing "no pain" on one end and "worst possible pain" on the other end. Participants are instructed to mark the line at the point that represents their current level of pain.

  8 weeks

• Endometrial Health Profile-30 Endometrial Health Profile

  The EHP-30 (Endometrial Health Profile-30) is a specific questionnaire designed to assess the impact of endometriosis on various aspects of a person's life. It is a self-report instrument that measures health-related quality of life in individuals with endometriosis.

  8 weeks

• Menstrual pattern Bleeding score MIQ questionnaire

  The Menstrual Pattern Bleeding Score MIQ (Menstrual Impact Questionnaire) questionnaire is a specific tool used to assess the impact of menstrual patterns and bleeding on individuals' lives. It is a self-report questionnaire that measures the severity and impact of menstrual symptoms and irregularities on various aspects of daily functioning.

  8 weeks

Study Arms (2)

Aerobic Exercise Group with Core Muscle strengthening Group

EXPERIMENTAL

Participants assigned to this group will undergo a combination of aerobic exercise and core muscle strengthening interventions. The aerobic exercise component will be similar to the first group, while additional exercises targeting the core muscles (abdomen, back, and pelvis) will be included.

Other: Aerobic Exercises with core Muscle strengthening

Aerobic Exercise without Core Muscle Strengthening Group

ACTIVE COMPARATOR

Participants assigned to this group will engage in aerobic exercise interventions

Other: Aerobic Exercise without Core Muscle Strengthening

Interventions

Aerobic Exercises with core Muscle strengthening OTHER

Participants assigned to this group will undergo a combination of aerobic exercise and core muscle strengthening interventions. The aerobic exercise component will be similar to the first group, while additional exercises targeting the core muscles (abdomen, back, and pelvis) will be included.

Aerobic Exercise Group with Core Muscle strengthening Group

Aerobic Exercise without Core Muscle Strengthening OTHER

Aerobic Exercise without Core Muscle Strengthening

Aerobic Exercise without Core Muscle Strengthening Group

Eligibility Criteria

• Age: 18 Years - 49 Years
• Gender Eligibility Details: Endometriosis occur during Menstrual Cycle
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Women diagnosed with endometriosis.(16)
• Age range (e.g., 18-49 years)
• Regular menstrual cycles or menstrual irregularities associated with endometriosis.
• Medically stable and cleared for participation in physical activity.
• No contraindications for aerobic exercise or core muscle strengthening

You may not qualify if:

• Pregnant individuals or those actively trying to conceive.
• Recent endometriosis-related surgeries/procedures
• Use of hormonal therapies/medications targeting endometriosis
• Severe endometriosis complications requiring immediate medical intervention
• Inability to engage in aerobic exercise.
• Significant cardiovascular/respiratory conditions
• Concurrent participation in another exercise/rehabilitation program

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Jinnah Hospital

Lahore, Punjab Province, 44000, Pakistan

Location

MeSH Terms

Conditions

Endometriosis

Interventions

Exercise

Condition Hierarchy (Ancestors)

Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Faiza Taufiq, PPDPT

  Riphah International University, Senior Lecturer

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 28, 2024
• First Posted: February 5, 2024
• Study Start: March 15, 2023
• Primary Completion: March 15, 2024
• Study Completion: March 15, 2024
• Last Updated: April 19, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)