Risk Identification of Long-term Complications

NCT06235866 | Enrolling By Invitation DMC

• 1 other identifier: 20230922
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators retrospectively analyze the clinical characteristics of severe COVID-19 in our hospital, and then establish a prediction model for long-term complications in patients with severe COVID-19, and strengthen follow-up to improve the prognosis of patients.

Conditions

Severe COVID-19

Keywords

COVID-19 Pneumonia; Long-term complications; Lung function

Outcome Measures

Primary Outcomes (2)

• Lung function

  Pulmonary function indicators improved gradually

  1 year

• Imaging of the lung

  The residual lesions in the lung were gradually absorbed

  1 year

Study Arms (1)

Follow-up cohort of patients with severe COVID-19

The scores of various scales, pulmonary function and imaging changes of patients with severe COVID-19 were collected at 3 months, 6 months and 12 months after rehabilitation and discharge.

Other: Pulmonary rehabilitation

Interventions

Pulmonary rehabilitation OTHER

According to the pulmonary rehabilitation guidelines, patients with severe COVID-19 were given regular rehabilitation treatment, including breathing exercises and physical rehabilitation exercises.

Follow-up cohort of patients with severe COVID-19

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with severe COVID-19 in our hospital from December 8, 2022 to January 31, 2023 were enrolled

You may qualify if:

• The patient met the diagnostic criteria for severe COVID-19

You may not qualify if:

• Pregnant women Patients who died of COVID-19 Patients younger than 18 years of age without pulmonary CT

Sponsors & Collaborators

• Wuhan Central Hospital: lead

Study Sites (1)

Follow-up of patients with severe COVID-19

Wuhan, 430000, China

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 8, 2023
• First Posted: February 1, 2024
• Study Start: February 1, 2023
• Primary Completion: September 30, 2024
• Study Completion: November 1, 2025
• Last Updated: May 8, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)