Corticosteroids in Severe COVID-19 (ASAP-ESICM/ESAIC Study)

NCT04866082 | Completed

• 1 other identifier: ASAP-ESICM/ESAIC
• Study Type: observational
• Target: 466
• Locations: 1 country
• Sites: 1

Brief Summary

Brief Summary: Administration of systemic corticosteroids for patients with severe forms of severe acute respiratory syndrome in coronavirus-2 (SARS-CoV-2) infection are recommended by several guidelines. In the very beginning of SARS-CoV-2 pandemic the early recommendation by professional organization was against routine use of corticosteroids for patients with coronavirus disease 2019 (COVID-19) ARDS, despite previous data and clinical practice for patients with refractory or severe form of acute respiratory distress syndrome (ARDS). But recently after publication of RECOVERY trial (Randomized Evaluation of Covid-19 Therapy, July 2020) and ensued metaanalysis of World Health Organization (WHO) working group, routine administration of systemic corticosteroids was revisited. However, there is an ongoing debate regarding evidence supporting the dose, type of administration (bolus vs. continuous infusion), timing and type of corticosteroids. Ongoing randomized controlled trials (RCTs) are challenging the recommendation of 6 mg of dexamethasone for all patients with severe form of COVID-19. Due to the dynamics of COVID-19 surges and rapid issuing of official recommendations, daily clinical practice of systemic corticosteroids administration can vary. An electronic evaluation form containing 20 questions will be sent to European Society of Intensive Care (ESICM) and European Society of Anaesthesiology and Intensive Care (ESAIC) members. Participants will be asked to describe their routine clinical practice regarding administration of systemic corticosteroids among patients with COVID-19 ARDS.

Conditions

Severe COVID-19

Keywords

COVID-19; ARDS; corticosteroids; critical care

Outcome Measures

Primary Outcomes (1)

• Administration of systemic corticosteroids among patients with COVID-19 ARDS practice in European countries - questionnaire (electronic survey)

  Electronic survey will be send to the European Society of intensive care (ESICM) members via email

  2 months

Study Arms (1)

ESICM and ESAIC members

questionnaire - Members of European Society of Intensive Care and European Society of Anaesthesiology and Intensive Care will obtain an electronic survey regarding their routine clinical practice of systemic corticosteroids administration among patients with COVID-19 ARDS

Other: questionnaire

Interventions

questionnaire OTHER

Members of European Society of Intensive Care and European Society of ANaesthesiology and Intensive care will obtain an electronic survey regarding their routine clinical practice of systemic corticosteroids administration among patients with COVID-19 ARDS

Also known as: electronic survey

ESICM and ESAIC members

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Members of European Society of Intensive Care Members of European Society of Anaesthesiology and Intensive Care (ESAIC)

You may qualify if:

• Members of European Society of Intensive Care (ESICM)
• Members of European Society of Anaesthesiology and Intensive Care (ESAIC)

You may not qualify if:

• not members of European Society of Intensive Care (ESICM)
• not members of European Society of Anaesthesiology and Intensive Care (ESAIC)

Sponsors & Collaborators

• Brno University Hospital: lead
• European Society of Intensive Care Medicine: collaborator
• European Society of Anaesthesiology and Intensive Care: collaborator

Study Sites (1)

Brno University Hospital

Brno, South Moravian, 62500, Czechia

Location

MeSH Terms

Conditions

COVID-19

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Jan Malaska, assoc. prof. MD., Ph.D.

  University Hospital Brno

  STUDY DIRECTOR

• Petr Stourac, prof.MD.Ph.D.

  Faculty of medicince Masaryk University and University Hospital Brno

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assoc.prof.MD,Ph.D

Study Record Dates

• First Submitted: April 26, 2021
• First Posted: April 29, 2021
• Study Start: May 30, 2021
• Primary Completion: June 14, 2022
• Study Completion: June 30, 2022
• Last Updated: February 22, 2023

Record last verified: 2023-02

Locations

CZ (1)