The Effect of Covered Eye Walking on Electroencephalogram in Stroke Patients Compared With Open Eye Walking

NCT06234618 | Suspended

• 1 other identifier: ZD2022065
• Study Type: observational
• Target: 5
• Locations: 1 country
• Sites: 1

Brief Summary

Post-stroke walking abnormalities present significant rehabilitation challenges. Visual deprivation training has been shown to be more effective than open-eye training. The investigators intend to examine the changes in electroencephalography patterns in stroke patients during visually deprived walking tasks. The stroke participants will be fitted with a brain cap. The participants will walk with their eyes open for 60 seconds, and then their eyes will be blindfolded as they continue walking for another 60 seconds. Electroencephalography will monitor the signals in real-time during both walks.

Conditions

Stroke

Keywords

Electroencephalography; walking; visual deprivation

Outcome Measures

Primary Outcomes (2)

• phase locking value

  used to evaluate the phase synchronization relationship between two signals.

  Real-time monitoring of electroencephalography data will occur while participants are walking. The Time Frame for data collection will encompass the entire duration of each participant's walking session, which lasts for 60 seconds.

• phase lag Index

  evaluate the degree of phase synchronization and the symmetry of neural oscillatory

  Real-time monitoring of electroencephalography data will occur while participants are walking. The Time Frame for data collection will encompass the entire duration of each participant's walking session, which lasts for 60 seconds.

Study Arms (1)

stroke patients

Stroke patients who can walk without assistance in their daily life.

Other: visual deprivation

Interventions

visual deprivation OTHER

A group of patients walking with eyes open and walking with visual deprivation.

stroke patients

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

stroke patients in a hospital inpatient unit

You may qualify if:

• Clinical diagnosis of stroke
• Disease duration of more than 14 days
• Ability to walk at least 10 m without assistance,

You may not qualify if:

• Visual impairment
• Severe cognitive impairment

Sponsors & Collaborators

• Nanjing Medical University: lead

Study Sites (1)

Geriatric Hospital of Nanjing Medical University

Nanjing, Jiangsu, China

Location

Related Publications (1)

• Oliveira AS, Schlink BR, Hairston WD, Konig P, Ferris DP. Restricted vision increases sensorimotor cortex involvement in human walking. J Neurophysiol. 2017 Oct 1;118(4):1943-1951. doi: 10.1152/jn.00926.2016. Epub 2017 Jul 5.

  PMID: 28679843 BACKGROUND

Related Links

• In this paper, the electroencephalography changes of normal people during visual deprivation walking were studied

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Xia Li Zhang, doctor

  Geriatric Hospital of Nanjing Medical University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Junior physiotherapist

Study Record Dates

• First Submitted: January 9, 2024
• First Posted: January 31, 2024
• Study Start: February 28, 2024
• Primary Completion: June 30, 2024
• Study Completion: June 30, 2024
• Last Updated: April 12, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR
• Time Frame: Three months after publication.
• Access Criteria: Request from the researchers by email.

Locations

CN (1)