NCT06234202

Brief Summary

In-season pitch volume have been shown to relate to arm soreness in collegiate baseball players. Arm soreness is a common ailment following a pitching appearance due to the adaptation to soft tissue in response to a repetitive load to the throwing arm. Specifically, ongoing and accumulated fatigue and soreness to the flexor pronator mass region of the arm may be a predecessor for UCL injury. Different recovery modalities such as a bioactive fabric sleeve may give pitchers a recovery advantage throughout a baseball season. The primary purpose of this study is to determine if there is a difference in subjective soreness of the flexor pronator mass the day following a game pitching appearance using a sleeve with bioactive fabric which potentially improves cellular function versus a control sleeve.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
13

participants targeted

Target at below P25 for not_applicable

Timeline
13mo left

Started Feb 2024

Longer than P75 for not_applicable

Geographic Reach
1 country

6 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress68%
Feb 2024Jun 2027

First Submitted

Initial submission to the registry

January 22, 2024

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 31, 2024

Completed
16 days until next milestone

Study Start

First participant enrolled

February 16, 2024

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2027

Last Updated

February 27, 2026

Status Verified

May 1, 2025

Enrollment Period

3.3 years

First QC Date

January 22, 2024

Last Update Submit

February 24, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Subjective Soreness Score

    Subjective soreness questionnaires to rank soreness, tightness, and discomfort of the medial forearm on a 1 to 10 scale will be collected throughout the baseball seasons.

    Baseline through 6 months

Study Arms (2)

Bioactive Sleeve then Control Sleeve

EXPERIMENTAL

Each pitcher will be instructed to sleep with the assigned sleeve on the throwing arm after each game that he pitches

Device: Bioactive SleeveDevice: Control Sleeve

Control Sleeve then Bioactive Sleeve

EXPERIMENTAL

Each pitcher will be instructed to sleep with the assigned sleeve on the throwing arm after each game that he pitches

Device: Bioactive SleeveDevice: Control Sleeve

Interventions

Pitchers will wear a bioactive sleeve immediately post-game through overnight.

Bioactive Sleeve then Control SleeveControl Sleeve then Bioactive Sleeve

Pitchers will wear a non-bioactive sleeve immediately post-game through overnight.

Bioactive Sleeve then Control SleeveControl Sleeve then Bioactive Sleeve

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Stanford Baseball Player

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

University of California, Davis

Davis, California, 95616, United States

Location

University of San Diego

San Diego, California, 92110, United States

Location

Stanford University

Stanford, California, 94305, United States

Location

University of Florida

Gainesville, Florida, 32611, United States

Location

University of Virginia

Charlottesville, Virginia, 22903, United States

Location

University of Washington

Seattle, Washington, 98195, United States

Location

Study Officials

  • Michael Freehill, MD

    Stanford University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

January 22, 2024

First Posted

January 31, 2024

Study Start

February 16, 2024

Primary Completion (Estimated)

June 1, 2027

Study Completion (Estimated)

June 1, 2027

Last Updated

February 27, 2026

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Locations