NCT06223633

Brief Summary

The PK Papyrus Covered Coronary Stent System is a coronary stent being used at Methodist Dallas Medical Center for patients with coronary perforations.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
41

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 4, 2020

Completed
2.8 years until next milestone

Study Start

First participant enrolled

August 10, 2023

Completed
6 months until next milestone

First Posted

Study publicly available on registry

January 25, 2024

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2025

Completed
Last Updated

November 21, 2024

Status Verified

January 1, 2024

Enrollment Period

2 years

First QC Date

November 4, 2020

Last Update Submit

November 18, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Determining the number of the unanticipated adverse events related to the use of PK Papyrus Coronary Stent Graft System

    Number of patients with PK Papyrus being treated for acute perforations of native coronary arteries and bypass grafts in vessels.

    Up to 10 years

  • Number of patients with the device

    number of patients with success coronary artery and bypass grafts

    10 years

Study Arms (1)

PK Papyrus Covered Coronary Stent System

EXPERIMENTAL

PK Papyrus Covered Coronary Stent System has been approved for use in the treatment of free perforations, defined as free contrast extravasation into the pericardium, in native coronary vessels or saphenous vein bypass grafts greater than or equal to 2.75mm in diameter.

Device: PK Papyrus Covered Coronary Stent System

Interventions

PK Papyrus Covered Coronary Stent System has been approved for use in the treatment of free perforations, defined as free contrast extravasation into the pericardium, in native coronary vessels or saphenous vein bypass grafts greater than or equal to 2.75mm in diameter.

PK Papyrus Covered Coronary Stent System

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with acute perforations of native coronary arteries and coronary bypass grafts in vessels 2.5 to 5.0 mm in diameter

You may not qualify if:

  • Patients in whom antiplatelet agents or anticoagulation therapy is contraindicated.
  • Patients with a known allergy or hypersensitivity to amorphous silicon carbide or any other compound of the system (siloxane-based polyurethane, L-605 cobalt chromium alloy including tungsten and nickel).
  • Lesions that cannot be reached or treated with the system.
  • Lesions with threatened or abrupt closure during attempted pre-dilation prior to stent implantation.
  • Risk of treatment-related occlusion of vital coronary artery side branches.
  • Uncorrected bleeding disorders.
  • Allergy to contrast media.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Methodist Dallas Medical Center

Dallas, Texas, 75201, United States

RECRUITING

MeSH Terms

Conditions

Coronary Disease

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular Diseases

Study Officials

  • Luis Bowen, M.D.

    The Methodist Hospital Research Institute

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Colette Ngo Ndjom, M.S.

CONTACT

Zaid Haddadin, M.S.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 4, 2020

First Posted

January 25, 2024

Study Start

August 10, 2023

Primary Completion

August 1, 2025

Study Completion

August 1, 2025

Last Updated

November 21, 2024

Record last verified: 2024-01

Locations