Health Behavior Management Program for Patients With Coronary Heart Disease

NCT07330882 | Enrolling By Invitation

• 1 other identifier: FirstAHBBMC
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Coronary artery disease (CAD) is a major chronic condition severely impacting population health in China. Our previous cohort studies revealed a high comorbidity rate between CAD and frailty, suggesting their interrelated equivalence as clinical syndromes with shared risk factors. In recent years, pilot integrated health management initiatives in China have demonstrated promising outcomes, yet evidence remains scarce regarding patients with concurrent CAD and frailty-a critical gap needing urgent resolution to achieve the "Healthy China 2030" strategic goals. Building on prior research, this project aims to systematically evaluate existing management models for patients with CAD and frailty, develop a tailored health management framework, and implement it in clinical settings through empirical studies. The model will be optimized according to regional and demographic variations, leveraging cardiac rehabilitation centers, exercise-based interventions, and internet-enabled technologies to enhance coordinated care. By improving exercise efficacy, mitigating frailty progression, and enhancing quality of life, this initiative seeks to establish a robust chronic disease management system. The findings will provide evidence for formulating regional health policy and insurance strategies in Anhui Province, ultimately improving standardized management rates for chronic diseases.

Conditions

Coronary Disease

Keywords

Myocardial Ischemia; Cardiac rehabilitation; Quality of life; Frailty

Outcome Measures

Primary Outcomes (2)

• 6MWD

  Measuring the maximum distance within 6 minutes.

  1month,3 months, 6 months

• The MOS item short from health survey

  Quality of life was assessed using the 36-Item Short Form Health Survey questionnaire

  1month,3 months, 6 months

Secondary Outcomes (7)

• Frailty

  1month,3 months, 6 months

• Grip strength

  1month,3 months, 6 months

• Gait speed

  1month,3 months, 6 months

• Physical activity level

  1month,3 months, 6 months

• Systolic pressure/Diastolic pressure

  1month,3 months, 6 months

Study Arms (2)

Intervention group

EXPERIMENTAL

The intervention consists of two parts: Health management model: Establish a "hospital-home" full-process health management service chain based on mobile health. Firstly, cardiac specialist nurses conduct a comprehensive assessment of each patient's cardiac rehabilitation status and implement individualized interventions. The specific intervention procedures are: "Assess the patient's current condition and capabilities - Promote the patient's awareness of the current situation - Develop and revise the cardiac rehabilitation plan - Supervise the implementation of the cardiac rehabilitation plan."

Behavioral: Exercise rehabilitation plan and health management model for patients with coronary heart disease and frailty based on mobile health technology

Control group

ACTIVE COMPARATOR

During the patient's hospital stay and after discharge, cardiovascular internal medical staff provide them with routine medical,nursing services and health education. In terms of basic drug treatment, the principles of secondary prevention for coronary heart disease should be followed. Routine nursing care and health education were delivered through verbal instruction and the "317 Nursing Education Platform." They were also advised to maintain a healthy lifestyle and participate in appropriate physical activities.

Behavioral: Exercise rehabilitation plan and health management model for patients with coronary heart disease and frailty based on mobile health technology

Interventions

Exercise rehabilitation plan and health management model for patients with coronary heart disease and frailty based on mobile health technology BEHAVIORAL

The development, application and evaluation of an innovative health management model for patients with coronary heart disease and frailty based on the "cardiac rehabilitation center" framework, exercise rehabilitation, and new technologies such as "mobile health".

Control group; Intervention group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of Coronary heart disease;
• Proficiency in smartphone use;
• Absence of visual, auditory, cognitive, or motor impairments.

You may not qualify if:

• Inability or unwillingness to provide informed consent;
• Physical or cognitive limitations preventing app operation;
• Inability to attend in-person follow-up visits;
• Concurrent severe comorbidities or malignancies, such as severe valvular heart disease, New York Heart Association class IV heart failure, severe aortic regurgitation, cancer, end-stage renal or liver disease;
• Any other condition that could potentially impede exercise participation.

Sponsors & Collaborators

• The First Affiliated Hospital of Bengbu Medical University: lead

Study Sites (1)

The First Affiliated Hospital of Bengbu Medical University

Bengbu, China

Location

MeSH Terms

Conditions

Coronary Disease; Myocardial Ischemia; Frailty

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Tong Zhou

  The First Affiliated Hospital of Bengbu Medical University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: November 17, 2025
• First Posted: January 9, 2026
• Study Start: October 20, 2024
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 30, 2027
• Last Updated: January 9, 2026

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)