NCT06223386

Brief Summary

Obesity stands as a significant health concern of the 21st century. The prevalence of obesity is steadily rising worldwide, and Taiwan is no exception, with nearly four to five out of ten individuals facing issues of overweight or obesity. Additionally, approximately 1.5% of adults suffer from morbid obesity. Presently, lifestyle interventions focusing on body control have shown limited success in maintaining an ideal weight and body composition, and they are predominantly applied within clinical settings for managing morbidly obese patients. In response to the transformations brought about by the 3C era in connecting with the public, an effective online intervention approach holds promising potential but still requires development and validation. This project endeavors to revolve around "cultivating a healthy lifestyle" by creating educational materials on weight reduction. These materials will encompass various aspects such as dietary habits, physical activity, and daily routines, all designed to impart online lifestyle education. To facilitate the intervention, the investigators plan to employ the application "Cofit" developed by the Cofit Healthcare Inc., targeting individuals with weight reduction needs. Furthermore, the investigators aim to collect research data for the analysis of intervention effectiveness. Over a three to six-month intervention period, the research participants will receive multifaceted lifestyle education through the online app. Certified nutritionists, trained under the program, will interact with the participants online, guiding them to make changes in their diet, physical activity, and daily routines. The ultimate goal is to help the participants achieve effective weight reduction and maintain a healthy body weight in the long term.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 12, 2024

Completed
13 days until next milestone

First Posted

Study publicly available on registry

January 25, 2024

Completed
1 month until next milestone

Study Start

First participant enrolled

February 26, 2024

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2024

Completed
Last Updated

August 13, 2024

Status Verified

August 1, 2024

Enrollment Period

7 months

First QC Date

January 12, 2024

Last Update Submit

August 12, 2024

Conditions

Outcome Measures

Primary Outcomes (3)

  • Achievement rate of healthy body weight at Month 3 and 6.

    The number of participants whose weight will be reduced to within the range of a personal BMI equal to 22 among all participants.

    Baseline, Month 3 and 6

  • Change from baseline in fat percent at Month 3 and 6.

    Baseline, Month 3 and 6

  • Change from baseline in diet quality at Month 3 and 6.

    Diet quality is estimated according to the daily intake of nutrients and the distribution of the six food groups, with a qualified food frequency questionnaire. The six food groups include: 1. Whole grains and starchy vegetables 2. Protein foods: soybeans, fish, eggs, and meat 3. Vegetables 4. Fruits 5. Dairy 6. Oils, nuts \& seeds.

    Baseline, Month 3 and 6

Secondary Outcomes (2)

  • Change from baseline in physical activity at Month 3 and 6.

    Baseline, Month 3 and 6

  • Change from baseline in sleep quality at Month 3 and 6.

    Baseline, Month 3 and 6

Study Arms (4)

Traditional model

PLACEBO COMPARATOR

Designed course A with 3-month consultation with the dietitians

Behavioral: Designed on-line course A with 3-month consultation with the dietitian

Multi-oriented lifestyle education

EXPERIMENTAL

Designed course B with 3-month consultation with the dietitians

Behavioral: Designed on-line course B with 3-month consultation with the dietitian

Multi-oriented lifestyle education with dietary assessment

EXPERIMENTAL

Designed course B with 3-month consultation with the dietitians + 3-month daily dietary assessment by the dietitians

Behavioral: Designed on-line course B with 3-month consultation with the dietitians + 3-month daily dietary assessment by the dietitians

Multi-oriented lifestyle education with longer period of dietary assessment

EXPERIMENTAL

Designed course B with 6-month consultation with the dietitians + 6-month daily dietary assessment by the dietitians

Behavioral: Designed on-line course B with 6-month consultation with the dietitians + 6-month daily dietary assessment by the dietitians

Interventions

Educational materials on weight reduction will be provided at the beginning of the 3-month intervention. Participants can consult with the dietitian via the APP on their mobile phones during the intervention period. These materials will encompass dietary and physical activity guidelines by the government in Taiwan.

Traditional model

Educational materials on weight reduction will be provided every weekday for 8 weeks. Participants can consult with the dietitian via the APP on their mobile phones during the 3-month intervention period. These materials will encompass various aspects such as dietary habits, physical activity, and daily routines, all designed to impart online lifestyle education.

Multi-oriented lifestyle education

Educational materials on weight reduction will be provided every weekday for 8 weeks. Participants can consult with the dietitian via the APP on their mobile phones during the 3-month intervention period. These materials will encompass various aspects such as dietary habits, physical activity, and daily routines, all designed to impart online lifestyle education. In addition, dietitians assess participants' daily diet for 3 months.

Multi-oriented lifestyle education with dietary assessment

Educational materials on weight reduction will be provided every weekday for 8 weeks. Participants can consult with the dietitian via the APP on their mobile phones during the 6-month intervention period. These materials will encompass various aspects such as dietary habits, physical activity, and daily routines, all designed to impart online lifestyle education. In addition, dietitians assess participants' daily diet for 6 months.

Multi-oriented lifestyle education with longer period of dietary assessment

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • BMI between 24 and 35

You may not qualify if:

  • cancer
  • hospitalization
  • pregnancy
  • depression
  • currently taking weight loss drugs
  • unwilling to give up meal replacement for weight loss
  • unable to cooperate with the data collection and intervention guide of this study
  • stage III kidney disease or above
  • diabetes
  • taking medication
  • participation in previous weight loss courses of Qunjian Technology Company

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute of Biomedical Sciences, Academia Sinica

Taipei, 115, Taiwan

Location

MeSH Terms

Conditions

OverweightObesity

Interventions

Referral and Consultation

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Professional PracticeOrganization and AdministrationHealth Services Administration

Study Officials

  • Wen-Harn Pan, Ph.D.

    Institute of Biomedical Sciences, Academia Sinica

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Distinguished Research Fellow

Study Record Dates

First Submitted

January 12, 2024

First Posted

January 25, 2024

Study Start

February 26, 2024

Primary Completion

September 30, 2024

Study Completion

September 30, 2024

Last Updated

August 13, 2024

Record last verified: 2024-08

Locations