NCT05620667

Brief Summary

The aim of this study is to investigate the effects of immature ponkan (Citrus reticulate) extract on body weight and body fat in overweight and obese adults.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 28, 2022

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

November 10, 2022

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 17, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2023

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2023

Completed
Last Updated

November 17, 2022

Status Verified

November 1, 2022

Enrollment Period

6 months

First QC Date

November 10, 2022

Last Update Submit

November 10, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change from baseline body weight at week 8

    Compared the difference of body weight between the week 8 and 0.

    Week 0, Week 8

Secondary Outcomes (1)

  • Change from baseline body fat at week 8

    Week 0, Week 8

Study Arms (3)

placebo

PLACEBO COMPARATOR

Placebo 25mL, without any ingredients of immature ponkan extract. Drink 25mL for once, and once a day.

Dietary Supplement: placebo

immature ponkan (Citrus reticulate) extract

EXPERIMENTAL

Immature ponkan (Citrus reticulate) extract 25 mL, drink 25mL for once, and once a day.

Dietary Supplement: immature ponkan (Citrus reticulate) extract

immature ponkan (Citrus reticulate) extract with time restricted feeding

EXPERIMENTAL

Immature ponkan (Citrus reticulate) extract 25 mL, drink 25mL for once, and once a day, adding time restricted feeding.

Dietary Supplement: immature ponkan (Citrus reticulate) extractBehavioral: time restricted feeding

Interventions

Drink 25mL for once, and once a day.

immature ponkan (Citrus reticulate) extractimmature ponkan (Citrus reticulate) extract with time restricted feeding
placeboDIETARY_SUPPLEMENT

Drink 25mL for once, and once a day.

placebo

Controlling a shortened period of time for eating within 8 hour each day.

immature ponkan (Citrus reticulate) extract with time restricted feeding

Eligibility Criteria

Age20 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • male or female
  • aged 20-60 years old
  • body mass index is greater than or equal to 24 kg/m2, or body fat more than 30%

You may not qualify if:

  • Subjects diagnosed with cancer and on curative care.
  • Subjects diagnosed with heart disease and on curative care.
  • Subjects who use other drugs whose pharmacological effects may affect the experiment or may aggravate the effects of the drug.
  • Subjects with systemic infection requiring antibiotics.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chung Shan Medical University

Taichung, South, 402, Taiwan

RECRUITING

MeSH Terms

Conditions

OverweightObesity

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Yu-Jou Chien, PhD student

    Chung Shan Medical University

    PRINCIPAL INVESTIGATOR
  • Ying-Ching Feng, MS student

    Chung Shan Medical University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Chin-Lin Hsu, Professor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 10, 2022

First Posted

November 17, 2022

Study Start

October 28, 2022

Primary Completion

April 30, 2023

Study Completion

August 31, 2023

Last Updated

November 17, 2022

Record last verified: 2022-11

Locations