NCT06222528

Brief Summary

Depression is a leading cause of illness and disability in teenagers. Longer duration of untreated depression (DUD) is associated with greater severity, poorer outcome, and cognitive impairment. Stigma toward people with depression has been identified as a barrier to seeking help; therefore, reducing stigma toward young people at depressive risk could enhance their receptivity to seeking treatment. Social contact is a form of interpersonal contact with members of the stigmatized group and the most effective type of intervention for improvement in stigma-related knowledge and attitudes. In a prior study, the investigators developed short video interventions to reduce stigma and increase treatment seeking among adolescents with depression. The videos feature adolescent protagonists varied by race/ethncitiy and gender (Black girl, Black boy, White girl, White boy, Hispanic girl, Hispanic boy, nonbinary or transgender adolescent) who will share their experiences with depression, challenges, and recovery process. The investigators would like to conduct a randomized controlled trial (RCT) to test the efficacy of these tailored videos as compared to a video control condition (which provides information about depression and how to seek help but does not include a personal story) on reducing self-stigma and increasing help-seeking intentions and behavior at baseline, post, 2 week follow-up, and 4 week follow-up among adolescents ages 14-18 recruited via Cloudresearch. The videos will be shown again at 2 week follow-up.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 16, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 24, 2024

Completed
4 months until next milestone

Study Start

First participant enrolled

June 3, 2024

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 17, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 17, 2024

Completed
Last Updated

September 4, 2024

Status Verified

September 1, 2024

Enrollment Period

3 months

First QC Date

January 16, 2024

Last Update Submit

September 3, 2024

Conditions

Outcome Measures

Primary Outcomes (8)

  • Depression Stigma

    The Depression Stigma Scale (DSS) is a self-report scale comprised of two 9-item subscales measuring participants' personal beliefs about depression and participants' beliefs about others' attitudes (Griffiths et al., 2004). The current study will only utilize the personal beliefs subscale. Each item is rated on a 5-point Likert scale ranging from strongly disagree (1) to strongly agree (5). Scores range from 9 to 45. Higher scores indicate more stigma.

    Baseline

  • Depression Stigma

    The Depression Stigma Scale (DSS) is a self-report scale comprised of two 9-item subscales measuring participants' personal beliefs about depression and participants' beliefs about others' attitudes (Griffiths et al., 2004). The current study will only utilize the personal beliefs subscale. Each item is rated on a 5-point Likert scale ranging from strongly disagree (1) to strongly agree (5). Scores range from 9 to 45. Higher scores indicate more stigma.

    Post (immediately after the videos are shown)

  • Depression Stigma

    The Depression Stigma Scale (DSS) is a self-report scale comprised of two 9-item subscales measuring participants' personal beliefs about depression and participants' beliefs about others' attitudes (Griffiths et al., 2004). The current study will only utilize the personal beliefs subscale. Each item is rated on a 5-point Likert scale ranging from strongly disagree (1) to strongly agree (5). Scores range from 9 to 45. Higher scores indicate more stigma.

    2 week follow-up

  • Depression Stigma

    The Depression Stigma Scale (DSS) is a self-report scale comprised of two 9-item subscales measuring participants' personal beliefs about depression and participants' beliefs about others' attitudes (Griffiths et al., 2004). The current study will only utilize the personal beliefs subscale. Each item is rated on a 5-point Likert scale ranging from strongly disagree (1) to strongly agree (5). Scores range from 9 to 45. Higher scores indicate more stigma.

    4 week follow-up

  • Attitude Towards Seeking Professional Psychological Help

    Treatment seeking intentions will be measured using three items from the Attitudes Towards Seeking Professional Psychological Help Scale (ATSPPHS) Scale (Elhai et al., 2008). Items include: 'I might want to have psychological counselling in the future', 'I would want to get psychological help if I were worried or upset for a long period of time' and 'A person with an emotional problem is not likely to solve it alone; he or she is more likely to solve it with professional help'. Responses range from 1 (disagree) to 4 (agree). Total scores range from 3 to 12 with higher scores indicating higher treatment seeking intentions.

    Baseline

  • Attitude Towards Seeking Professional Psychological Help

    Treatment seeking intentions will be measured using three items from the Attitudes Towards Seeking Professional Psychological Help Scale (ATSPPHS) Scale (Elhai et al., 2008). Items include: 'I might want to have psychological counselling in the future', 'I would want to get psychological help if I were worried or upset for a long period of time' and 'A person with an emotional problem is not likely to solve it alone; he or she is more likely to solve it with professional help'. Responses range from 1 (disagree) to 4 (agree). Total scores range from 3 to 12 with higher scores indicating higher treatment seeking intentions.

    Post (immediately after the videos are shown)

  • Attitude Towards Seeking Professional Psychological Help

    Treatment seeking intentions will be measured using three items from the Attitudes Towards Seeking Professional Psychological Help Scale (ATSPPHS) Scale (Elhai et al., 2008). Items include: 'I might want to have psychological counselling in the future', 'I would want to get psychological help if I were worried or upset for a long period of time' and 'A person with an emotional problem is not likely to solve it alone; he or she is more likely to solve it with professional help'. Responses range from 1 (disagree) to 4 (agree). Total scores range from 3 to 12 with higher scores indicating higher treatment seeking intentions.

    2 week follow-up

  • Attitude Towards Seeking Professional Psychological Help

    Treatment seeking intentions will be measured using three items from the Attitudes Towards Seeking Professional Psychological Help Scale (ATSPPHS) Scale (Elhai et al., 2008). Items include: 'I might want to have psychological counselling in the future', 'I would want to get psychological help if I were worried or upset for a long period of time' and 'A person with an emotional problem is not likely to solve it alone; he or she is more likely to solve it with professional help'. Responses range from 1 (disagree) to 4 (agree). Total scores range from 3 to 12 with higher scores indicating higher treatment seeking intentions.

    4 week follow-up

Secondary Outcomes (13)

  • Emotional engagement

    Post (immediately after the videos are shown

  • Emotional engagement

    2 week follow-up

  • Treatment related stigma

    Baseline

  • Treatment related stigma

    Post (immediately after the videos are shown)

  • Treatment related stigma

    2 week follow-up

  • +8 more secondary outcomes

Study Arms (8)

Brief video intervention (Black Girl)

EXPERIMENTAL

A brief social contact-based video with a Black girl protagonist

Behavioral: Brief video intervention (Black Girl)

Brief video intervention (Black Boy)

EXPERIMENTAL

A brief social contact-based video with a Black boy protagonist

Behavioral: Brief video intervention (Black Boy)

Brief video intervention (Latinx Girl)

EXPERIMENTAL

A brief social contact-based video with a Latinx girl protagonist

Behavioral: Brief video intervention (Latinx Girl)

Brief video intervention (Latinx Boy)

EXPERIMENTAL

A brief social contact-based video with a Latinx boy protagonist

Behavioral: Brief video intervention (Latinx Boy)

Brief video intervention (White Girl)

EXPERIMENTAL

A brief social contact-based video with a White girl protagonist

Behavioral: Brief video intervention (White Girl)

Brief video intervention (White Boy)

EXPERIMENTAL

A brief social contact-based video with a White boy protagonist

Behavioral: Brief video intervention (White Boy)

Brief video intervention (Nonbinary or transgender)

EXPERIMENTAL

A brief social contact-based video with a nonbinary or transgender protagonist

Behavioral: Brief video intervention (Nonbinary or transgender)

Control

ACTIVE COMPARATOR

A brief video control condition with psychoeducation on depression and help seeking

Behavioral: Control Condition

Interventions

A brief social contact-based video. The video presented a young Black girl, a professional actor, sharing her scripted personal story of struggles with depression and raising themes of recovery and hope.

Brief video intervention (Black Girl)

A brief social contact-based video. The video presented a young Black boy, a professional actor, sharing his scripted personal story of struggles with depression and raising themes of recovery and hope.

Brief video intervention (Black Boy)

A brief social contact-based video. The video presented a young Latinx girl, a professional actor, sharing her scripted personal story of struggles with depression and raising themes of recovery and hope.

Brief video intervention (Latinx Girl)

A brief social contact-based video. The video presented a young Latinx boy, a professional actor, sharing his scripted personal story of struggles with depression and raising themes of recovery and hope.

Brief video intervention (Latinx Boy)

A brief social contact-based video. The video presented a young White girl, a professional actor, sharing her scripted personal story of struggles with depression and raising themes of recovery and hope.

Brief video intervention (White Girl)

A brief social contact-based video. The video presented a young White boy, a professional actor, sharing his scripted personal story of struggles with depression and raising themes of recovery and hope.

Brief video intervention (White Boy)

A brief social contact-based video. The video presented a young nonbinary or transgender adolescent, a professional actor, sharing their scripted personal story of struggles with depression and raising themes of recovery and hope.

Brief video intervention (Nonbinary or transgender)

A video that will provide information about depression and how to seek help but does not include a personal story.

Control

Eligibility Criteria

Age14 Years - 18 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Ages 14-18
  • English speaking
  • US Residents

You may not qualify if:

  • Age less than 14 or greater than 18
  • Non-English speaking
  • Non-US Resident

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York State Psychiatric Institute

New York, New York, 10032, United States

Location

Related Publications (5)

  • Griffiths KM, Christensen H, Jorm AF, Evans K, Groves C. Effect of web-based depression literacy and cognitive-behavioural therapy interventions on stigmatising attitudes to depression: randomised controlled trial. Br J Psychiatry. 2004 Oct;185:342-9. doi: 10.1192/bjp.185.4.342.

    PMID: 15458995BACKGROUND
  • Elhai JD, Schweinle W, Anderson SM. Reliability and validity of the Attitudes Toward Seeking Professional Psychological Help Scale-Short Form. Psychiatry Res. 2008 Jun 30;159(3):320-9. doi: 10.1016/j.psychres.2007.04.020. Epub 2008 Apr 22.

    PMID: 18433879BACKGROUND
  • de Vreede T, Andel SA, de Vreede GJ, Spector P, Singh V, Padmanabhan B. What is engagement and how do we measure it? Toward a domain independent definition and scale. Proceedings of the 52nd Hawaii International Conference on System Sciences. 2019, Hawaii. p. 749-758.

    BACKGROUND
  • Clement S, Brohan E, Jeffery D, Henderson C, Hatch SL, Thornicroft G. Development and psychometric properties the Barriers to Access to Care Evaluation scale (BACE) related to people with mental ill health. BMC Psychiatry. 2012 Jun 20;12:36. doi: 10.1186/1471-244X-12-36.

    PMID: 22546012BACKGROUND
  • Brenner RE, Colvin KF, Hammer JH, Vogel DL. Using Item Response Theory to Develop Revised (SSOSH-7) and Ultra-Brief (SSOSH-3) Self-Stigma of Seeking Help Scales. Assessment. 2021 Jul;28(5):1488-1499. doi: 10.1177/1073191120958496. Epub 2020 Sep 25.

    PMID: 32975438BACKGROUND

MeSH Terms

Conditions

Social StigmaMental DisordersAdolescent BehaviorDepression

Condition Hierarchy (Ancestors)

Social BehaviorBehaviorBehavioral Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Clinical Psychiatry

Study Record Dates

First Submitted

January 16, 2024

First Posted

January 24, 2024

Study Start

June 3, 2024

Primary Completion

August 17, 2024

Study Completion

August 17, 2024

Last Updated

September 4, 2024

Record last verified: 2024-09

Data Sharing

IPD Sharing
Will not share

Locations