Detection of the Effect of Irrigation Fluid on Extravascular Lung Water in Patients Undergoing TRUP Using Bedside Lung Ultrasound

NCT06220734 | Unknown

• 1 other identifier: US in Anesthesia
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

Early detection of fluid accumulation in alveolar, interstitial, and intracellular compartments of the lung due to intravascular absorption of irrigation fluid of TURP guided by lung ultrasound by detection of sonographic B lines.

Conditions

TUR Syndrome; Anesthesia

Outcome Measures

Primary Outcomes (1)

• Incidence of intraoperative lung congestion quantified by number of sonographic B-lines in anterolateral lung ultrasound scan in patients undergoing TURP

  Early detection of fluid accumulation in alveolar, interstitial, and intracellular compartments of the lung due to intravascular absorption of irrigation fluid of TURP guided by lung ultrasound by detection of sonographic B lines

  1 year

Interventions

transurethral resection of the prostate PROCEDURE

transurethral resection of the prostate for indicated patients then US was done for early detection of fluid accumulation in the lungs

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

men attended at assuit university hospital, for underwent transurethral resection of the prostate and fulfilled inclusion criteria

You may qualify if:

• ASA Class I, II or III adult patients of age group 18-65 years.
• Patient undergoing TURP.

You may not qualify if:

• Patients unable to provide written consent.
• Patients less than 18 years or above 65 years.
• ASA Class IV.
• Patients previously diagnosed to suffer from interstitial lung disease.
• patients who will receive intraoperative diuretics

Sponsors & Collaborators

• Assiut University: lead

Related Publications (2)

• Gravenstein D. Transurethral resection of the prostate (TURP) syndrome: a review of the pathophysiology and management. Anesth Analg. 1997 Feb;84(2):438-46. doi: 10.1097/00000539-199702000-00037. No abstract available.

  PMID: 9024044 BACKGROUND

• Gupta K, Rastogi B, Jain M, Gupta PK, Sharma D. Electrolyte changes: An indirect method to assess irrigation fluid absorption complications during transurethral resection of prostate: A prospective study. Saudi J Anaesth. 2010 Sep;4(3):142-6. doi: 10.4103/1658-354X.71505.

  PMID: 21189849 BACKGROUND

Biospecimen

Retention: SAMPLES WITHOUT DNA

None Retained

MeSH Terms

Interventions

Transurethral Resection of Prostate

Intervention Hierarchy (Ancestors)

Prostatectomy; Urologic Surgical Procedures, Male; Urologic Surgical Procedures; Urogenital Surgical Procedures; Surgical Procedures, Operative

Central Study Contacts

Monica Nabil ELcellini

CONTACT

+201095548405; monicanabil19@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Doctor

Study Record Dates

• First Submitted: January 14, 2024
• First Posted: January 24, 2024
• Study Start: April 5, 2024
• Primary Completion: April 5, 2025
• Study Completion: August 5, 2025
• Last Updated: January 24, 2024

Record last verified: 2024-01