Effect of Ozone Therapy on Aerobic Exercise Performance

NCT06217549 | Completed

• 1 other identifier: ozone therapy, performance
• Study Type: interventional
• Target: 17
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to investigate the effect of the ozone therapy applied using the major autohemotherapy method on exercise performance in male healthy individuals. The main question's aims to answer are:

• Is ozone therapy applied with the major autohemotherapy method increase the performance?
• Is ozone therapy applied with the major autohemotherapy method improve the recovery after exercise?
• Participants are asked to continue the same exercise program throughout the study. They were given 10 sessions of ozone therapy over 6 weeks. Researchers compared the before and after treatment performance and recovery data.

Conditions

Ozone Therapy; Exercise Performance

Outcome Measures

Primary Outcomes (4)

• VO2max

  maximum oxygen consumption, indicator of aerobic capacity, cardiopulmonary exercise tests performed twice for each participant

  just before the first ozone therapy session and immediately after the last ozone therapy session

• exercise duration

  duration of cardiopulmonary exercise test

  just before the first ozone therapy session and immediately after the last ozone therapy session

• Modified Borg Scale

  Modified Borg Scale is used to measure the perceived fatigue level. The participants were asked to rate their perceived fatigue on a scale of 1-10. It was expressed as 1 'no fatigue' and 10 'extreme fatigue (exhaustion).

  just before the first ozone therapy session and immediately after the last ozone therapy session

• Lactate levels

  lactate levels at the end of the each 3-minute grades of each cardiopulmonary exercise tests

  just before the first ozone therapy session and immediately after the last ozone therapy session

Study Arms (1)

healthy participants

EXPERIMENTAL

healthy, physically active people will be included the study.

Other: ozone therapy

Interventions

ozone therapy OTHER

Medical ozone is a mixture of pure ozone gas (0.05-5%) and pure oxygen (99.95-95%). It is produced from pure medical oxygen by medical ozone generators. It is applied to the participants 10 sessions by the intravenous method.

healthy participants

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• male
• healthy
• aged between 18-35 years old

You may not qualify if:

• suffering from a low back or lower extremity injury or surgical operation in the last one year
• having cardiovascular disease
• having glucose 6 phosphate dehydrogenase enzyme deficiency
• having chronic metabolic disease
• having hyperthyroidism, mental and psychological problems.

Sponsors & Collaborators

• Istanbul University: lead

Study Sites (1)

Şensu Dinçer

Istanbul, 34093, Turkey (Türkiye)

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: medical doctor

Study Record Dates

• First Submitted: January 9, 2024
• First Posted: January 22, 2024
• Study Start: August 12, 2019
• Primary Completion: January 31, 2020
• Study Completion: January 31, 2020
• Last Updated: January 23, 2024

Record last verified: 2024-01

Locations

TU (1)