NCT06216795

Brief Summary

The investigators aim to investigate the association between renal volume measured through pre-donation CT auto-segmentation and postoperative renal function of both donors and recipients. After establishing the statistical significance of the association, the investigators intend to create and validate predictive models for renal function at surgery, 1 year, and 3 years postoperatively, incorporating various factors known to contribute to renal function deterioration.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 24, 2022

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

January 11, 2024

Completed
11 days until next milestone

First Posted

Study publicly available on registry

January 22, 2024

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 23, 2024

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2024

Completed
Last Updated

January 24, 2024

Status Verified

January 1, 2024

Enrollment Period

1.9 years

First QC Date

January 11, 2024

Last Update Submit

January 22, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Prediction models for the residual renal function of donors and the graft kidney function of recipient after live donor kidney transplantation

    1 and 3 years after transplantation

Study Arms (1)

kidney transplant group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

live kidney donors and paired their recipients.

You may qualify if:

  • live donor kidney transplant

You may not qualify if:

  • donors without preoperative enhanced CT image

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul National University Hospital

Seoul, 110-744, South Korea

RECRUITING

Related Publications (1)

  • Jo EA, Lee J, Moon S, Kim JS, Han A, Ha J, Kim YC, Min S. The role of artificial intelligence measured preoperative kidney volume in predicting kidney function loss in elderly kidney donors: a multicenter cohort study. Int J Surg. 2024 Nov 1;110(11):7169-7176. doi: 10.1097/JS9.0000000000002030.

Central Study Contacts

Sangil Min, MD, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 11, 2024

First Posted

January 22, 2024

Study Start

May 24, 2022

Primary Completion

April 23, 2024

Study Completion

December 31, 2024

Last Updated

January 24, 2024

Record last verified: 2024-01

Locations