NCT06203964

Brief Summary

The aim of this study is to generate evidence regarding organizing pneumonia in lung transplant recipients.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
280

participants targeted

Target at P75+ for all trials

Timeline
1mo left

Started Jul 2023

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress95%
Jul 2023Jul 2026

Study Start

First participant enrolled

July 7, 2023

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

January 2, 2024

Completed
10 days until next milestone

First Posted

Study publicly available on registry

January 12, 2024

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2025

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2026

Expected
Last Updated

January 12, 2024

Status Verified

January 1, 2024

Enrollment Period

2 years

First QC Date

January 2, 2024

Last Update Submit

January 2, 2024

Conditions

Organizing PneumoniaLung Transplant Rejection

Outcome Measures

Primary Outcomes (1)

  • Prevalence of organizing pneumonia

    01.01.2012-01.06.2023

Secondary Outcomes (24)

  • Body Mass Index

    date of organizing pneumonia

  • Forced expiratory volume in 1 second

    1 year before and after organizing pneumonia

  • Total lung capacity

    1 year before and after organizing pneumonia

  • Vital capacity

    1 year before and after organizing pneumonia

  • Prevalence of primary graft dysfunction

    01.01.2012-01.06.2023

  • +19 more secondary outcomes

Interventions

No interventionOTHER

No intervention

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All lung transplant recipients treated in the lung transplantation department of the USZ will be included in this analysis with documented tissue sampling or autopsy between 01.01.2012 and 01.06.2023

You may qualify if:

  • All lung transplant recipients treated in the lung transplantation department of the USZ will be included in this analysis with documented tissue sampling or autopsy between 01.01.2012 and 01.06.2023

You may not qualify if:

  • Denied general consent or any statement verbal or in writing by patient that precludes research

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Zurich

Zurich, 8091, Switzerland

Location

MeSH Terms

Conditions

Organizing Pneumonia

Condition Hierarchy (Ancestors)

Bronchiolitis ObliteransBronchiolitisBronchitisBronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 2, 2024

First Posted

January 12, 2024

Study Start

July 7, 2023

Primary Completion

July 1, 2025

Study Completion (Estimated)

July 1, 2026

Last Updated

January 12, 2024

Record last verified: 2024-01

Locations

CH(1)