Effect of Quadriceps Muscle on Physical Outcome Measures in Women With Rheumatoid Arthritis
Evaluation of Morphologic Parameters of Quadriceps Muscle Predicting Disease Activity, Physical Performance and Quality of Life in Women With Rheumatoid Arthritis
1 other identifier
observational
102
1 country
1
Brief Summary
Studies have reported that individuals with Rheumatoid Arthritis have a smaller muscle cross-sectional area, pennation angle and muscle thickness than healthy controls. Sarcopenia may decrease physical performance and quality of life in individuals with RA. Therefore, morphologic changes in the quadriceps femoris muscle due to sarcopenia may help us to gain insight into physical function and quality of life. This study aims to evaluate the predictive capacity of morphologic characteristics of the quadriceps femoris muscle for disease activity, physical performance, and quality of life in women with Rheumatoid Arthritis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Dec 2023
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 25, 2023
CompletedFirst Submitted
Initial submission to the registry
December 26, 2023
CompletedFirst Posted
Study publicly available on registry
January 9, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 25, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 25, 2025
CompletedJanuary 23, 2024
January 1, 2024
2 years
December 26, 2023
January 20, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Vastus lateralis muscle length
Vastus Lateralis muscle length will be measured bilaterally by Ultrasound.
10 minutes
Interventions
The morphological characteristics of the quadriceps muscle of the participants will be assessed using ultrasound.
Eligibility Criteria
Female participants between the ages of 18-65 who have been diagnosed with Rheumatoid Arthritis for at least 3 years and who come to Afyonkarahisar Health Sciences University Physical Therapy and Rehabilitation outpatient clinic will be included in the study.
You may qualify if:
- years old
- Female participants with a confirmed diagnosis of RA for at least 3 years according to the 2010 American College of Rheumatology (ACR) criteria
- Presence of sarcopenia
You may not qualify if:
- Presence of fractures, burns or lesions in the area to be measured
- Presence of any neuromuscular, cardiovascular or metabolic disease,
- Individuals with knee endoprosthesis,
- Inability to walk
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Afyonkarahisar Health Sciences University
Afyonkarahisar, 03030, Turkey (Türkiye)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
ERDAL HORATA, PhD
Afyonkarahisar Health Sciences University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PhD; Lecturer; Principal Investigator
Study Record Dates
First Submitted
December 26, 2023
First Posted
January 9, 2024
Study Start
December 25, 2023
Primary Completion
December 25, 2025
Study Completion
December 25, 2025
Last Updated
January 23, 2024
Record last verified: 2024-01