The Effects of Pilates Training on Exercise Capacity and Respiratory Muscle Performance in Patients With Rheumatoid Arthritis

NCT05240326 | Unknown

• 1 other identifier: 2021-730
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with significant functional impairment and increased risk for cardiovascular and pulmonary disease. Along with pharmacological therapy, exercise seems to be a very promising intervention to improve disease-related outcomes, including functional capacity and systemic manifestations. Despite the fact that aerobic and strengthening exercises have been shown to be useful in patients with RA, there have been limited research on the effects of pilates training. Therefore, we aimed to investigate the effect of clinical pilates training on exercise capacity, respiratory and peripheral muscle strength, respiratory muscle endurance, respiratory function, pain, balance, core stability, dyspnea, functional status, fatigue, quality of life, depression and anxiety in patients with RA.

Conditions

Rheumatoid Arthritis

Keywords

rheumatoid arthritis; respiratory muscle strength; respiratory muscle endurance; exercise capacity

Outcome Measures

Primary Outcomes (4)

• Respiratory muscle strength

  Maximal inspiratory and expiratory muscle strength will be evaluated using mouth pressure device.

  First day

• Respiratory muscle endurance

  It will be assessed using an incremental threshold loading test, in which patients began with a load of 30% of maximum inspiratory pressure and increased by 10% every 2 minutes.

  First day

• Functional exercise capacity

  It will be evaluated with 6-minute walking test according to the American Thoracic Society and European Respiratory Society criteria.

  First day

• Pulmonary functions contains dynamic lung volumes

  Spirometry will be used to perform pulmonary function testing in accordance with the American Thoracic Society and European Respiratory Society guidelines.

  First day

Secondary Outcomes (9)

• Peripheral muscle strength

  Second day

• Pain level

  First day

• Balance

  Second day

• Core stability

  Second day

• Dyspnea

  First day

Study Arms (2)

exercise training group

ACTIVE COMPARATOR

Clinical pilates exercises

Other: exercise training group

control training group

SHAM COMPARATOR

Relaxation exercises

Other: control training group

Interventions

exercise training group OTHER

All exercise program will be applied during supervised session by a physiotherapist. Clinical pilates exercises will be performed three days in a week. Treatment will continue an hour in per session for 8 weeks. The program consisted of 10 minutes warm-up exercises, clinical pilates-based exercises on mat for 40 minutes and 10 minutes relaxation and stretching exercises.

exercise training group

control training group OTHER

The control group will be followed up as a home program by giving the relaxation exercises. Patients will be asked to do the exercises regularly for 3 days/week, 1 sessions/day, for eight weeks. Patients in the control group will be followed up by phone once a week.

control training group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years old
• Being diagnosed according to the American College of Rheumatology (ACR)/EULAR 2010 rheumatoid arthritis diagnostic criteria
• under standard medications

You may not qualify if:

• orthopedic or neurological disease with a potential to affect functional capacity
• have problems that can prevent evaluation
• have a neurological problem that may cause hearing or vision impairment
• changes in medical treatment in the last 3 months
• have high disease activity score (DAS-28\>3.2)

Sponsors & Collaborators

• Gazi University: lead

Study Sites (1)

Gazi University

Ankara, Turkey (Türkiye)

Location

Related Publications (4)

• Yentur SB, Atas N, Ozturk MA, Oskay D. Comparison of the effectiveness of pilates exercises, aerobic exercises, and pilates with aerobic exercises in patients with rheumatoid arthritis. Ir J Med Sci. 2021 Aug;190(3):1027-1034. doi: 10.1007/s11845-020-02412-2. Epub 2020 Oct 22.

  PMID: 33094465 BACKGROUND

• Byrnes K, Wu PJ, Whillier S. Is Pilates an effective rehabilitation tool? A systematic review. J Bodyw Mov Ther. 2018 Jan;22(1):192-202. doi: 10.1016/j.jbmt.2017.04.008. Epub 2017 Apr 26.

  PMID: 29332746 BACKGROUND

• Silva HJA, Lins CAA, Nobre TTX, de Sousa VPS, Caldas RTJ, de Souza MC. Mat Pilates and aquatic aerobic exercises for women with fibromyalgia: a protocol for a randomised controlled blind study. BMJ Open. 2019 Feb 19;9(2):e022306. doi: 10.1136/bmjopen-2018-022306.

  PMID: 30782866 BACKGROUND

• Kucukdeveci AA. Nonpharmacological treatment in established rheumatoid arthritis. Best Pract Res Clin Rheumatol. 2019 Oct;33(5):101482. doi: 10.1016/j.berh.2019.101482. Epub 2020 Jan 25.

  PMID: 31987686 BACKGROUND

MeSH Terms

Conditions

Arthritis, Rheumatoid

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases

Study Officials

• Deran Oskay, Prof

  Gazi University

  STUDY DIRECTOR

Central Study Contacts

Selin Bayram, Msc

CONTACT

+905327001805; selinbayram94@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 5, 2022
• First Posted: February 15, 2022
• Study Start: March 15, 2022
• Primary Completion: March 1, 2024
• Study Completion: March 15, 2024
• Last Updated: March 3, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)