Effect of Hot Water Immersion on Heart Rate Variability and Glucose
HWI
1 other identifier
interventional
28
1 country
1
Brief Summary
Heat therapy has been shown to reduce risk of various diseases, including heart disease, alzheimers, and pneumonia, as well as all-cause mortality . A previous study found heating a single hand lowers postprandial blood glucose levels with a magnitude similar to certain exercise interventions such as 40 minutes of slow walking We propose that heating both feet and heating both legs up to the calves will result in similar glucose reductions in a dose response manner.Overview To determine the effect of heating both feet to the ankles and heating both legs to the calves on postprandial blood glucose
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Mar 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 2, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2021
CompletedFirst Submitted
Initial submission to the registry
December 21, 2023
CompletedFirst Posted
Study publicly available on registry
January 5, 2024
CompletedJanuary 8, 2024
January 1, 2024
12 months
December 21, 2023
January 4, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Blood Glucose
120 min
Secondary Outcomes (1)
Heart rate variability
120 min
Study Arms (3)
Thermoneutral
NO INTERVENTIONParticipant sits at room temperature during an oral glucose tolerance test
Feet heating
EXPERIMENTALParticipant sits with feet placed in hot water during an oral glucose tolerance test
Calf heating
EXPERIMENTALParticipant sits with legs, up to calves, placed in hot water during an oral glucose tolerance test
Interventions
Eligibility Criteria
You may qualify if:
- to 65 years
You may not qualify if:
- previously diagnosed diabetes
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
San Diego State University
San Diego, California, 92182, United States
Related Publications (3)
Laukkanen JA, Laukkanen T, Kunutsor SK. Cardiovascular and Other Health Benefits of Sauna Bathing: A Review of the Evidence. Mayo Clin Proc. 2018 Aug;93(8):1111-1121. doi: 10.1016/j.mayocp.2018.04.008.
PMID: 30077204BACKGROUNDKimball AL, McCue PM, Petrie MA, Shields RK. Whole body heat exposure modulates acute glucose metabolism. Int J Hyperthermia. 2018;35(1):644-651. doi: 10.1080/02656736.2018.1516303. Epub 2018 Oct 10.
PMID: 30303421BACKGROUNDMoore J, Kressler J, Buono MJ. Hand heating lowers postprandial blood glucose concentrations: A double-blind randomized controlled crossover trial. Complement Ther Med. 2020 Mar;49:102280. doi: 10.1016/j.ctim.2019.102280. Epub 2019 Dec 12.
PMID: 32147036BACKGROUND
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
December 21, 2023
First Posted
January 5, 2024
Study Start
March 2, 2020
Primary Completion
March 1, 2021
Study Completion
March 1, 2021
Last Updated
January 8, 2024
Record last verified: 2024-01
Data Sharing
- IPD Sharing
- Will not share