NCT06192134

Brief Summary

The Investigators are investigating a continuous passive motion device to exercise the knee of young children with arthrogryposis after they have had knee surgery.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5

participants targeted

Target at below P25 for not_applicable

Timeline
12mo left

Started Jun 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 20, 2023

Completed
16 days until next milestone

First Posted

Study publicly available on registry

January 5, 2024

Completed
2.4 years until next milestone

Study Start

First participant enrolled

June 1, 2026

Expected
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2027

1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2027

Last Updated

February 13, 2026

Status Verified

June 1, 2025

Enrollment Period

11 months

First QC Date

December 20, 2023

Last Update Submit

February 11, 2026

Conditions

Arthrogryposis

Outcome Measures

Primary Outcomes (1)

  • range of motion

    knee range of motion

    2 weeks

Study Arms (1)

CPM group

EXPERIMENTAL

group receiving CPM therapy

Device: CPM device

Interventions

CPM deviceDEVICE

CPM brace

CPM group

Eligibility Criteria

Age3 Years - 7 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Children with arthrogryposis
  • Children between 3 and 7 years of age
  • Children who have had recent knee surgery

You may not qualify if:

  • Children older than 7
  • Children unable to cooperate with protocol steps

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Arthrogryposis

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesMuscular DiseasesMusculoskeletal AbnormalitiesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Tariq Rahman

CONTACT

302 651 6831trahman@nemours.org

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Model Details: Pilot study of intervention compared to historic controls
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Research Engineer

Study Record Dates

First Submitted

December 20, 2023

First Posted

January 5, 2024

Study Start (Estimated)

June 1, 2026

Primary Completion (Estimated)

May 1, 2027

Study Completion (Estimated)

June 1, 2027

Last Updated

February 13, 2026

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share