Functional Magnetic Resonance Imaging Study on the Role of Awareness in Visual Perception in Healthy Adult Subjects.

NCT06183775 | Completed

• 1 other identifier: VISCON-01
• Study Type: observational
• Target: 62
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of the study concerns the investigation of the role of awareness in visual perception, highlighting the brain systems involved during non-processing Aware of stimuli belonging to different semantic categories. Specifically, the theoretical perspective of reference is that of the so-called "grounded cognition", according to which the representation of the concepts of semantic knowledge is conveyed by information sensorimotor and affective, introspective and social states. The main objective is therefore to evaluate whether the meaning of the stimulus can be extracted in the absence of awareness, investigating the neural response in the brain regions known to be involved in the conscious processing of stimuli belonging to the semantic categories in question. To this end, two different experimental paradigms were implemented. A first paradigm aimed at investigating the unconscious representation of semantic knowledge in the context of language, therefore using visual stimuli in lexical mode (words). A second paradigm aimed at investigating the same phenomena in the field of visual perception of objects in space, using stimuli in iconic mode (images).

Conditions

Magnetic Resonance

Outcome Measures

Primary Outcomes (1)

• Magnetic resonance imaging for 62 healthy volunteers for measure the role of consciousness in visual perception.

  The role of consciousness in visual perception, highlighting the brain areas involved during the processing of stimuli belonging to different semantic categories.

  2 years

Eligibility Criteria

• Age: 20 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Volunteers, enlisted among the students and workers of the San Raffaele Hospital and other universities.

You may qualify if:

• aged between 20 and 65;
• Italian mother tongue.

You may not qualify if:

• clinical evidence of significant psychiatric or systemic neurological pathologies.

Sponsors & Collaborators

• IRCCS San Raffaele: lead

Study Sites (1)

Irccs San Raffaele

Milan, 20132, Italy

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor in Diagnostic Imaging and Radiotherapy Faculty of Medicine and Surgery, Vita-Salute San Raffaele University Director, Department of Nuclear Medicine, IRCCS Ospedale San Raffaele

Study Record Dates

• First Submitted: December 12, 2023
• First Posted: December 28, 2023
• Study Start: November 6, 2017
• Primary Completion: May 4, 2019
• Study Completion: May 4, 2019
• Last Updated: December 28, 2023

Record last verified: 2023-12

Data Sharing

• IPD Sharing: Will not share

Locations

IT (1)