High-resolution CE-MRA of Children's Hip Joint

NCT05754905 | Completed

• 1 other identifier: CQMU-2023-2
• Study Type: observational
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to learn about the feasibility of enhanced three-dimensional water-selective cartilage (3D-WATSc) sequence in displaying the vessels of children's hip by magnetic resonance. The main questions it aims to answer are:

• Could the images of enhanced 3D-WATSc sequence show the healthy side hip joint vessels in children?
• Could the images of enhanced 3D-WATSc sequence show the vascular disease of the suffering side hip joint in children? Participants with unilateral hip disease will undergo the magnetic resonance examination including enhanced 3D-WATSc sequence. The pelvic plain film and magnetic resonance images will be collected and analysed. Researchers will compare the images of of the normal side with the images of the abnormal side to see if the enhanced 3D-WATSc sequence images could show the vascular disease of the suffering side hip joint in children?

Conditions

Hip; Vessels; Anomaly; Magnetic Resonance; Three-dimensional Water-selective Cartilage (3D-WATSc)

Outcome Measures

Primary Outcomes (3)

• The medial circumflex femoral artery (MCFA) and lateral circumflex femoral artery (LCFA) of the bilateral hip joint

  Morphology of the MCFA and LCFA of the bilateral hip joint

  1 day (Magnetic resonance examination end time)

• The branches of the MCFA and/or LCFA around the bilateral femoral neck

  Morphology of MCFA and/or LCFA branches around the bilateral femoral neck

  1 day (Magnetic resonance examination end time)

• The vessels of secondary ossification center and/or cartilaginous vascular canal in bilateral femoral head

  Morphology of the vessels and cartilaginous vascular canal in bilateral femoral head

  1 day (Magnetic resonance examination end time)

Study Arms (2)

Normal hip joint

The normal side of patients with hip joint disease

Other: Magnetic resonance examination

Abnormal hip joint

The abnormal side of patients with hip joint disease

Other: Magnetic resonance examination

Interventions

Magnetic resonance examination OTHER

the two groups are underwent magnetic resonance examination including enhanced 3D-WATSc sequence

Abnormal hip joint; Normal hip joint

Eligibility Criteria

• Age: 6 Months - 14 Years
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children with hip disease from 2021-2022 in Children's Hospital of Chongqing Medical University

You may qualify if:

• Children aged 6 months-14 years who are diagnosed as hip disease after screening by pediatric orthopedic surgeon in Children's Hospital of Chongqing Medical University during the study period. The hip disease contain developmental dysplasia of the hip, Perthes disease, infection of the hip, inflammation of the hip, fracture of the hip, and Meyer's dysplasia.

You may not qualify if:

• patients with bilateral hip joint disease; patients with claustrophobia;Patients with metal implants (such as pacemaker implantation)

Sponsors & Collaborators

• Children's Hospital of Chongqing Medical University: lead

Study Sites (1)

Children's Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400014, China

Location

MeSH Terms

Conditions

Congenital Abnormalities

Condition Hierarchy (Ancestors)

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

• Yuxi Su, M.D.

  Children's Hospital of Chongqing Medical University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Orthopaedic Department

Study Record Dates

• First Submitted: February 23, 2023
• First Posted: March 6, 2023
• Study Start: January 1, 2021
• Primary Completion: December 30, 2022
• Study Completion: January 31, 2023
• Last Updated: March 6, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)