In Patients With Hip Dysplasia, Mid-Term Lower Extremities and Spine After Hip Arthroplasty Natural Course

NCT06176612 | Completed

• 1 other identifier: A10207
• Study Type: interventional
• Target: 33
• Locations: 1 country
• Sites: 1

Brief Summary

Patients with developmental hip dysplasia often present to the outpatient clinic in adulthood with hip pain due to progressive hip osteoarthritis. However, they may have complaints such as limping, lumbar lordosis, lower back pain, and leg length difference. Today, the best treatment option for these patients is hip arthroplasty. Hip arthroplasty causes a high rate of functional improvement and pain relief. According to the hip arthroplasty technique applied, improvement in lameness, leg length difference and spinal curvatures is expected. The aim of our study is to show the change in postoperative spine and lower extremity curvatures after hip arthroplasty in patients with advanced developmental hip dislocation.

Conditions

Total Hip Arthroplasty

Keywords

hip; Total hip arthroplasty; developmental hip dysplasia

Outcome Measures

Primary Outcomes (1)

• Mechanical axis deviation (MAD)

  the lower limb was defined as the distance from the center of the knee to the mechanical axis of the lower limb

  From enrollment to the end of treatment at 2 years

Secondary Outcomes (5)

• tibiofemoral angle (TFA)

  From enrollment to the end of treatment at 2 years

• The femoral offset (FO)

  From enrollment to the end of treatment at 2 years

• The hip-knee-ankle angle (HKA)

  From enrollment to the end of treatment at 2 years

• The lateral distal femoral angle (LDFA)

  From enrollment to the end of treatment at 2 years

• The medial proximal tibial angle (MPTA)

  From enrollment to the end of treatment at 2 years

Study Arms (1)

Patients with Crowe type 3 or Crowe type 4 hip dysplasia who underwent total hip replacement

EXPERIMENTAL

Procedure: total hip arthroplasty

Interventions

total hip arthroplasty PROCEDURE

Patients with Crowe type 3 or Crowe type 4 hip dysplasia who underwent hip replacement

Patients with Crowe type 3 or Crowe type 4 hip dysplasia who underwent total hip replacement

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with unilateral Crowe type 3 hip dysplasia
• Patients with unilateral Crowe type 4 hip dysplasia

You may not qualify if:

• Patients with unilateral Crowe type 1 hip dysplasia
• Patients with unilateral Crowe type 2 hip dysplasia
• History of previous surgery on the hip for which surgery is planned

Sponsors & Collaborators

• Bezmialem Vakif University: lead

Study Sites (1)

Bezmialem Vakıf University

Istanbul, Fatih, 34093, Turkey (Türkiye)

Location

Related Publications (3)

• Can A, Erdogan F, Yontar NS, Ovul Erdogan A, Erdem MN, Sarikaya IA. Spinopelvic alignment does not change after bilateral total hip arthroplasty in patients with bilateral Crowe type-IV developmental dysplasia of the hip. Acta Orthop Traumatol Turc. 2020 Nov;54(6):583-586. doi: 10.5152/j.aott.2020.19043.

  PMID: 33423988 RESULT

• Zhao HY, Kang PD, Shi XJ, Zhou ZK, Yang J, Shen B, Pei FX. Effects of Total Hip Arthroplasty on Axial Alignment of the Lower Limb in Patients with Unilateral Developmental Hip Dysplasia (Crowe type IV). J Arthroplasty. 2019 Oct;34(10):2406-2414. doi: 10.1016/j.arth.2019.04.028. Epub 2019 Apr 20.

  PMID: 31103361 RESULT

• Kocabiyik A, Misir A, Kizkapan TB, Yildiz KI, Kaygusuz MA, Alpay Y, Ezici A. Changes in Hip, Knee, and Ankle Coronal Alignments After Total Hip Arthroplasty With Transverse Femoral Shortening Osteotomy for Unilateral Crowe Type IV Developmental Dysplasia of the Hip. J Arthroplasty. 2017 Nov;32(11):3449-3456. doi: 10.1016/j.arth.2017.05.044. Epub 2017 Jun 1.

  PMID: 28641973 RESULT

MeSH Terms

Conditions

Developmental Dysplasia of the Hip

Interventions

Arthroplasty, Replacement, Hip

Condition Hierarchy (Ancestors)

Hip Dislocation; Joint Dislocations; Joint Diseases; Musculoskeletal Diseases; Musculoskeletal Abnormalities; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Arthroplasty, Replacement; Arthroplasty; Orthopedic Procedures; Surgical Procedures, Operative; Plastic Surgery Procedures; Prosthesis Implantation

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 10, 2023
• First Posted: December 19, 2023
• Study Start: April 15, 2021
• Primary Completion: November 15, 2023
• Study Completion: October 1, 2024
• Last Updated: April 1, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)