Evaluation of Patients With Diffuse Parenchymal Lung Diseases Regarding Frailty

NCT06171425 | Unknown

• 1 other identifier: GO 23/18
• Study Type: observational
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

There are very few studies in the literature examining the frailty levels of diffuse parenchymal lung disease (DPLD) patients and its effect on their functional status despite the high prevalance of frailty in patients with DPLD This observational study aims to learn about the relationship between frailty and functional capacity and balance in DPLD patients compared to healthy subjects.

Conditions

Diffuse Parenchymal Lung Disease; Frailty; Physical Inactivity

Outcome Measures

Primary Outcomes (1)

• frailty level

  evaluation of frailty level with Fried Frailty Criteria which are weight loss existence, muscle strength, physical activity (will be measured with International Physical Activity Questionnaire), mobility (will be measured by 4-meter walking test), and depression level. Fried frailty phenotype consists of five criteria: loss, exhaustion, physical inactivity, low hand grip strength, and slow walking speed. Patients who have three or more of these criteria are defined as frail, those who have one or two criteria, are defined as prefrail, and none of the criteria are defined as robust.

  1 time which will be in one day

Secondary Outcomes (11)

• comorbidity assesment

  1 time which will be in one day

• exercise capacity

  1 time which will be in one day

• balance measurement

  day 1

• posture analysis

  day 1

• posture related conditions measurement

  day 1

Study Arms (2)

DPAH group

patients with diffuse parenchymal lung diseases

control group

aged matched healthy patients

Eligibility Criteria

• Age: 30 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients referred by the department of chest diseases of Hacettepe university will be taken

You may qualify if:

• Being diagnosed with Diffuse parenchymal lung according to the American Thoracic Society/European Respiratory Society (ATS/ERS) criteria,
• Being between the ages of 30-65,
• Being literate,
• Being willing to participate in the research,
• Being clinically stable and having any accompanying comorbid conditions (such as hypertension, diabetes) under control,
• Not having any orthopedic, metabolic or neurological problems that may prevent evaluation of peripheral muscle strength, balance and exercise capacity.

You may not qualify if:

• Having recently experienced syncope,
• Having a history of unstable cardiovascular disease,
• Having been hospitalized due to exacerbation in the last 3 months,
• Having received pulmonary rehabilitation in the last 12 months,
• Having a neurological disease,
• Being dependent and using a walking aid while performing the person's daily life activities,
• Having a pacemaker,
• Having a diagnosis of lung cancer

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University, Health Sciences Faculty

Ankara, 06100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Lung Diseases, Interstitial; Frailty; Sedentary Behavior

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior

Central Study Contacts

AYNUR DEMIREL, Assoc. Prof.

CONTACT

+9053123051576; aynur.demirel@hacettepe.edu.tr

Aynur Demirel

CONTACT

05545295057; aynurdemirel629@hotmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PT, PhD, Assoc. Prof.

Study Record Dates

• First Submitted: October 30, 2023
• First Posted: December 14, 2023
• Study Start: December 25, 2023
• Primary Completion: January 1, 2024
• Study Completion: February 22, 2024
• Last Updated: December 19, 2023

Record last verified: 2023-12

Locations

TU (1)