Post-emergency Management of Patients With Transient Ischemic Attack

NCT06170034 | Completed

• 1 other identifier: PEC AIT 84
• Study Type: observational
• Target: 49
• Locations: 1 country
• Sites: 1

Brief Summary

A transient ischemic attack (TIA) is a momentary neurological dysfunction due to a brief cessation of blood flow to a region of the brain, resulting in typical signs of stroke (hemiplegia, aphasia, dysarthria), but whose clinical symptoms typically last less than an hour, with no visible lesion on imaging. This diagnosis remains difficult and is essentially based on the clinical judgment of the physician. Because a TIA can be a "pre-alarm" for stroke in 20-30% of cases, it needs to be treated appropriately and as early as possible in the emergency department. Stroke rates after untreated TIA are 5% within 48 hours, 10% within one month and 20% within one year. This risk is calculated using the ABCD² score which is based on the patient's risk factors and the clinical manifestations of TIA. Patients with a score ≥ 3 should be hospitalized as soon as possible for a complete medical evaluation. However, this score has not been scientifically validated, and several specialists agree that all TIAs should be evaluated immediately. Preventing stroke is a major public health issue because it is a serious, disabling and sometimes fatal disease. Given the seriousness of the progression from TIA to stroke, the French National Authority for Health has issued a series of management recommendations. However, in practice, these guidelines remain complicated to follow and patients management may vary and be more or less effective. Therefore, the aim of this study is to highlight the differences in how inpatients and outpatients are managed. Following these observations, solutions will be sought to make the care and management of these patients more efficient and more in line with recommendations.

Conditions

Transient Ischemic Attack

Keywords

Emergency; Cerebral RMI; Guidelines compliance

Outcome Measures

Primary Outcomes (1)

• Assess time between arrival in the emergency department for suspected TIA patients and MRI.

  Baseline

Secondary Outcomes (8)

• Time between arrival in the emergency department and MRI by departments.

  Baseline

• Time between arrival in the emergency department and MRI by ABCD² score.

  Baseline

• Percentage of patients with complete TIA management by departments.

  Baseline

• Hospitalization times according to care units

  Baseline

• Hospitalization times according to complete TIA management

  Baseline

Study Arms (1)

TIA patients

Behavioral: Satisfaction questionnaire; Other: Medical care questionnaire

Interventions

Satisfaction questionnaire BEHAVIORAL

Satisfaction questionnaire to assess how TIA patients feels about their medical care.

TIA patients

Medical care questionnaire OTHER

Recording appointments and results of examinations and consultations in TIA management

TIA patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with a diagnosis of TIA in the emergency department

You may qualify if:

• Patient over 18 years old.
• Consultation in the emergency department.
• Suspected TIA diagnosed by emergency physician.
• Duration of TIA symptoms \<1 hour.

You may not qualify if:

• Validation MRI performed prior to suspected TIA.
• Patient hospitalized for a condition other than TIA, including stroke.
• Patient referred to another hospital for further examination.
• Pregnant women.
• Patient unable to understand and answer a questionnaire.
• Patient under legal protection.

Sponsors & Collaborators

• Centre Hospitalier Henri Duffaut - Avignon: lead

Study Sites (1)

Centre Hospitalier d'Avignon

Avignon, France

Location

MeSH Terms

Conditions

Ischemic Attack, Transient; Emergencies

Condition Hierarchy (Ancestors)

Brain Ischemia; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Yohan Fouilhe, Medical Intern

  Centre Hospitalier d'Avignon, Service des urgences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 17, 2023
• First Posted: December 14, 2023
• Study Start: November 16, 2023
• Primary Completion: May 16, 2024
• Study Completion: June 16, 2024
• Last Updated: January 30, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)