NCT06169592

Brief Summary

The aim of the study is to improve the results of related transplantation of the right liver lobe by verifying the general predictors of the development of hemostatic system disorders and optimizing a comprehensive program for thrombohemorrhagic complications preventing.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
8mo left

Started Apr 2022

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress87%
Apr 2022Dec 2026

Study Start

First participant enrolled

April 22, 2022

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

December 5, 2023

Completed
8 days until next milestone

First Posted

Study publicly available on registry

December 13, 2023

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 14, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 16, 2026

Last Updated

December 30, 2025

Status Verified

July 1, 2025

Enrollment Period

4.6 years

First QC Date

December 5, 2023

Last Update Submit

December 29, 2025

Conditions

Liver CirrhosisLiver Transplant; Complications

Outcome Measures

Primary Outcomes (1)

  • Thrombosis of vascular anastomosis

    Thrombosis of arterial or venous anastomosis after intervention

    1 month

Secondary Outcomes (1)

  • Hemorrhagic complications

    1 month

Study Arms (1)

liver transplant group

Procedure: Liver transplantation

Interventions

Liver transplantationPROCEDURE

Related transplantation of the right lobe of the liver

liver transplant group

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with end stage liver cirrhosis who underwent living related liver transplantation.

You may qualify if:

  • Age over 18 years and up to 70 years;
  • End stage liver cirrhosis.

You may not qualify if:

  • Pregnancy;
  • Extrahepatic factors influencing systemic hemostasis;
  • Concomitant hematological diseases affecting the hemostatic system;
  • Severe concomitant disorders.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Republican specialized scientific and practical medical center of surgery named after academician V.Vakhidov

Tashkent, 100115, Uzbekistan

RECRUITING

MeSH Terms

Conditions

Liver Cirrhosis

Interventions

Liver Transplantation

Condition Hierarchy (Ancestors)

Liver DiseasesDigestive System DiseasesFibrosisPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Tissue TransplantationCell- and Tissue-Based TherapyBiological TherapyTherapeuticsDigestive System Surgical ProceduresSurgical Procedures, OperativeOrgan TransplantationTransplantation

Central Study Contacts

Azam Babadjanov, Professor

CONTACT

+998901751703azambabadjanov@gmail.com

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

December 5, 2023

First Posted

December 13, 2023

Study Start

April 22, 2022

Primary Completion (Estimated)

November 14, 2026

Study Completion (Estimated)

December 16, 2026

Last Updated

December 30, 2025

Record last verified: 2025-07

Locations

UZ(1)