NCT02126033

Brief Summary

Celiac disease is an autoimmune process that causes destructive changes in the epithel of the small bowel and it is also a pre-malignant state (e.g lymphoma). The aim of the study is to examine telomere length and other parameters of genetic instability from peripheral blood lymphocytes of patients with celiac disease compared with healthy controls.

Trial Health

50
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 27, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 29, 2014

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Last Updated

April 29, 2014

Status Verified

April 1, 2014

First QC Date

April 27, 2014

Last Update Submit

April 27, 2014

Conditions

Keywords

celiactelomeretelomerase

Outcome Measures

Primary Outcomes (1)

  • telomere length

    at entry, after 6 months of gluten-free diet

Study Arms (1)

celiac disease

EXPERIMENTAL
Procedure: take blood samples

Interventions

celiac disease

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients with celiac disease

You may not qualify if:

  • known malignancy
  • cannot sign informed consent
  • under age 18

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Celiac Disease

Condition Hierarchy (Ancestors)

Malabsorption SyndromesIntestinal DiseasesGastrointestinal DiseasesDigestive System DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
physician in gastroenterlogy institute

Study Record Dates

First Submitted

April 27, 2014

First Posted

April 29, 2014

Primary Completion

December 1, 2015

Last Updated

April 29, 2014

Record last verified: 2014-04