Oncological and Functional Outcomes in Lower Limb Osteosarcoma Pediatric Patient
Department of Orthopedic Oncology, The First Affiliated Hospital of Sun Yat-sen University
1 other identifier
observational
345
1 country
1
Brief Summary
Retrospective analysis of specific characteristics of complications and long-term oncological and function outcomes in lower-limb osteosarcoma pediatric patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2000
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2000
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 23, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
November 23, 2023
CompletedFirst Submitted
Initial submission to the registry
November 29, 2023
CompletedFirst Posted
Study publicly available on registry
December 8, 2023
CompletedDecember 8, 2023
December 1, 2023
23.9 years
November 29, 2023
December 6, 2023
Conditions
Outcome Measures
Primary Outcomes (8)
Overall Survival rate (OS)
Oncological outcomes
2000-2019
Progression-Free Survival rate (PFS)
Oncological outcomes
2000-2019
Local recurrence rate(LRR)
Oncological outcomes
2000-2019
Metastasis rate
Oncological outcomes
2000-2019
Final limb-salvage and amputation rate
Oncological outcomes
2000-2019
Prosthesis survival rate
Functional outcomes
2000-2019
Musculoskeletal Tumor Society (MSTS) score
Functional outcomes
2000-2019
Complications
Functional outcomes
2000-2019
Study Arms (5)
age groups
The general characteristic of patients and clinical data including age, Enneking stage, surgical methods, type of prosthesis, primary tumor location were recorded.
surgical methods
The general characteristic of patients and clinical data including age, Enneking stage, surgical methods, type of prosthesis, primary tumor location were recorded.
type of prosthesis
The general characteristic of patients and clinical data including age, Enneking stage, surgical methods, type of prosthesis, primary tumor location were recorded.
primary tumor location
The general characteristic of patients and clinical data including age, Enneking stage, surgical methods, type of prosthesis, primary tumor location were recorded.
Enneking stage
The general characteristic of patients and clinical data including age, Enneking stage, surgical methods, type of prosthesis, primary tumor location were recorded.
Interventions
Retrospective analysis
Eligibility Criteria
A retrospective analysis of 345 pediatric patients with lower-limb osteosarcoma admitted to our department between 2000 and 2019 was conducted.
You may qualify if:
- Diagnosed lower limb osteosarcoma patients under the age of 14;
- Performing tumor resection treatment in our hospital;
- There is complete clinical registration data available.
You may not qualify if:
- Not undergoing surgical treatment in our hospital;
- Age older than 14 years old;
- No available clinical registration data or lost follow-up patients;
- Non lower limb osteosarcoma patients.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Changye Zoulead
Study Sites (1)
Changye Zou
Guangzhou, Guangdong, 518010, China
Related Publications (1)
Xu M, Tu J, Huang Y, Wang B, Zhao Z, Lin T, Huang G, Yin J, Xie X, Shen J, Zou C. Comparison of oncological and functional outcomes in Lower-limb osteosarcoma pediatric patients: a large single-center retrospective cohort study. Int J Surg. 2024 Jul 1;110(7):4208-4220. doi: 10.1097/JS9.0000000000001340.
PMID: 38471042DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Clinical Professor
Study Record Dates
First Submitted
November 29, 2023
First Posted
December 8, 2023
Study Start
January 1, 2000
Primary Completion
November 23, 2023
Study Completion
November 23, 2023
Last Updated
December 8, 2023
Record last verified: 2023-12
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, ICF, CSR
- Time Frame
- SCI online. The datasets are available from the corresponding author on reasonable request.
- Access Criteria
- The datasets are available from the corresponding author (zouchy@mail.sysu.edu.cn) on reasonable request after SCI online.
The datasets are available from the corresponding author (zouchy@mail.sysu.edu.cn) on reasonable request after SCI online.