Key Insights

Highlights

Success Rate

75% trial completion

Published Results

33 trials with published results (14%)

Research Maturity

82 completed trials (34% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

11.7%

28 terminated out of 240 trials

Success Rate

74.5%

-12.0% vs benchmark

Late-Stage Pipeline

4%

9 trials in Phase 3/4

Results Transparency

40%

33 of 82 completed with results

Key Signals

33 with results75% success28 terminated

Data Visualizations

Phase Distribution

185Total
Not Applicable (20)
Early P 1 (6)
P 1 (76)
P 2 (74)
P 3 (8)
P 4 (1)

Trial Status

Completed82
Recruiting52
Unknown36
Terminated28
Active Not Recruiting21
Not Yet Recruiting11

Trial Success Rate

74.5%

Benchmark: 86.5%

Based on 82 completed trials

Clinical Trials (240)

Showing 20 of 20 trials
NCT04897321Phase 1Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT06638931Phase 2Recruiting

Agnostic Therapy in Rare Solid Tumors

NCT07129226Not ApplicableRecruitingPrimary

Musculoskeletal Cancers Remote Monitoring and Care

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT06465199Phase 1Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

NCT04616560Phase 2SuspendedPrimary

Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma

NCT06935409Phase 3Active Not RecruitingPrimary

Study of HS-20093 Versus Gemcitabine in Combination With Docetaxel in Treatment of Osteosarcoma After Previous Second-line Treatment Failure

NCT06541262Phase 1Recruiting

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

NCT07516353Not ApplicableNot Yet Recruiting

my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults

NCT02945800Phase 2CompletedPrimary

Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma

NCT06341712Phase 2TerminatedPrimary

Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma

NCT03721068Phase 1Recruiting

Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma

NCT05395741Phase 1Active Not RecruitingPrimary

Regorafenib in Patients With Refractory Primary Bone Tumors

NCT04571229UnknownPrimary

Expanded Access Use of L-MTP-PE for the Treatment of Osteosarcoma

NCT04833582Phase 1CompletedPrimary

A Study of Azenosertib (ZN-c3) in Combination With Gemcitabine in Subjects With Osteosarcoma

NCT03478462Phase 1Active Not Recruiting

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

NCT07479732Phase 1RecruitingPrimary

Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma

NCT07477457Phase 2RecruitingPrimary

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

NCT06384404RecruitingPrimary

Upfront Surgical Resection for Osteosarcoma

NCT06625190Phase 1Recruiting

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

Scroll to load more

Research Network

Activity Timeline