Key Insights

Highlights

Success Rate

75% trial completion

Published Results

33 trials with published results (14%)

Research Maturity

82 completed trials (34% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

11.5%

28 terminated out of 244 trials

Success Rate

74.5%

-12.0% vs benchmark

Late-Stage Pipeline

4%

9 trials in Phase 3/4

Results Transparency

40%

33 of 82 completed with results

Key Signals

33 with results75% success28 terminated

Data Visualizations

Phase Distribution

188Total
Not Applicable (21)
Early P 1 (7)
P 1 (77)
P 2 (74)
P 3 (8)
P 4 (1)

Trial Status

Completed82
Recruiting57
Unknown36
Terminated28
Active Not Recruiting21
Not Yet Recruiting10

Trial Success Rate

74.5%

Benchmark: 86.5%

Based on 82 completed trials

Clinical Trials (244)

Showing 20 of 20 trials
NCT06465199Phase 1Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

NCT07321912Phase 2RecruitingPrimary

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

NCT03900793Phase 1RecruitingPrimary

Losartan + Sunitinib in Treatment of Osteosarcoma

NCT02867592Phase 2Active Not Recruiting

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

NCT04616560Phase 1Suspended

Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Newly Diagnosed, Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

NCT06235125Phase 1RecruitingPrimary

Safety and Feasibility of Intraoperative Visualization With Cytalux in Children

NCT07628634Early Phase 1Recruiting

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

NCT07129226Not ApplicableRecruitingPrimary

Musculoskeletal Cancers Remote Monitoring and Care

NCT06492954Phase 1RecruitingPrimary

Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma

NCT07602049Phase 2Recruiting

Cryoablation Plus Camrelizumab for Advanced Soft Tissue Sarcoma

NCT04897321Phase 1Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

NCT03643133Phase 2Active Not RecruitingPrimary

Mifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients

NCT07593573Active Not RecruitingPrimary

the Exploration of MTAP Deletion in Osteosarcoma by Immunohistochemistry

NCT01790152Recruiting

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

NCT05492682Phase 1Recruiting

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

NCT06064682RecruitingPrimary

An Organoid-based Functional Precision Medicine Trial in Osteosarcoma

NCT04571229UnknownPrimary

Expanded Access Use of L-MTP-PE for the Treatment of Osteosarcoma

NCT06500819Phase 1Recruiting

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors

NCT05235165Phase 3Recruiting

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

NCT07052383Phase 1RecruitingPrimary

Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas

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