Unplanned ICU Readmission for Pediatric Liver Transplantation

NCT06162260 | Unknown

• 1 other identifier: gaoleiqing
• Study Type: observational
• Target: 1,575
• Locations: 0 countries
• Sites: N/A

Brief Summary

To explore the risk factors of unplanned return to Intensive Care Unit (ICU) in pediatric liver transplant recipients, and to provide data support for the transfer of pediatric liver transplant recipients from ICU after surgery, so as to avoid unplanned ICU return and reduce the mortality of patients during hospitalization.

Conditions

Liver Transplantation

Keywords

readdmission;ICU;transplantation

Outcome Measures

Primary Outcomes (1)

• Unplanned return to the ICU

  ICU re-entry occurred within the same hospital cycle after the first ICU transfer after liver transplantation

  01/01/2018-31/12/2021

Study Arms (2)

observation group

(1) Liver transplantation was performed between January 1, 2019 and December 31, 2019; (2) Age \< 18 years; (3) The patient was admitted to ICU for the first time due to postoperative monitoring after liver transplantation; (4) Survival on first transfer from ICU.

Procedure: ICU readmission

matched group

(1) Liver transplantation was performed between January 1, 2019 and December 31, 2019; (2) Age \< 18 years; (3) The patient was admitted to ICU for the first time due to postoperative monitoring after liver transplantation; (4) survive the first transfer from ICU; (5) No ICU re-entry occurred in the same hospitalization period after liver transplantation.

Interventions

ICU readmission PROCEDURE

Children who underwent liver transplantation at Renji Hospital, Shanghai Jiao Tong University School of Medicine from January 1, 2018 to December 31, 2021 and were transferred out of ICU for the first time during the same hospitalization cycle.

observation group

Eligibility Criteria

• Age: 1 Month - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Children who underwent liver transplantation at Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from Jan 1, 2018 to Dec 31, 2021.

You may qualify if:

• (1) Liver transplantation was performed from January, 2018 to December, 31, 2021.21;
• (2) Age \< 18 years;
• (3) The patient was admitted to ICU for the first time due to postoperative monitoring after liver transplantation;
• (4) Survival on first transfer from ICU.

You may not qualify if:

• (1) Death during ICU stay after liver transplantation;
• (2) non-first-time recipients of liver transplantation;
• (3) Patients with complex conditions who were transferred to ICU for life support (such as mechanical ventilation, CRRT, etc.) before operation;
• (4) Patients admitted to ICU by appointment for surgical reasons.
• (5) Patients forcibly transferred from ICU.

Sponsors & Collaborators

• RenJi Hospital: lead

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 1, 2023
• First Posted: December 8, 2023
• Study Start: December 1, 2023
• Primary Completion: November 29, 2024
• Study Completion: December 28, 2024
• Last Updated: December 8, 2023

Record last verified: 2023-12