NCT06160674

Brief Summary

This work aims to evaluate whether the segmentation of vowel recordings collected from patients diagnosed with COPD and healthy control groups can increase the classification precision of machine learning techniques.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
68

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 28, 2023

Completed
Same day until next milestone

Study Start

First participant enrolled

November 28, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 7, 2023

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2024

Completed
Last Updated

November 25, 2024

Status Verified

November 1, 2024

Enrollment Period

11 months

First QC Date

November 28, 2023

Last Update Submit

November 22, 2024

Conditions

Keywords

SegmentationClassificationCOPDMachine Learning

Outcome Measures

Primary Outcomes (1)

  • Classification performance

    Binary classification performance of the ML algorithm on each segment.

    30 weeks

Study Arms (2)

COPD

30 COPD participants, 16 Female and 14 Male.

Other: COPD

HC

38 HC participants, 20 Female and 18 Male.

Other: COPD

Interventions

COPDOTHER

A vowel segmentation data set consisting of information from COPD and HC groups will be used to experiment with the classification performance of several Machine Learning techniques on different segments of a vowel recording.

Also known as: HC
COPDHC

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Data will be collected from participants 18 years old and older with and without COPD diagnosis will be recruited.

You may qualify if:

  • being 18 years old and older.

You may not qualify if:

  • being under 18 years old and older.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Blekinge Institute of Technology

Karlskrona, Blekinge County, 37179, Sweden

Location

Related Publications (1)

  • Idrisoglu A, Moraes ALD, Cheddad A, Anderberg P, Jakobsson A, Berglund JS. Vowel segmentation impact on machine learning classification for chronic obstructive pulmonary disease. Sci Rep. 2025 Mar 22;15(1):9930. doi: 10.1038/s41598-025-95320-3.

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Johan Sanmartin Berglund, MD, PhD

    Blekinge Institute of Technology

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 28, 2023

First Posted

December 7, 2023

Study Start

November 28, 2023

Primary Completion

October 30, 2024

Study Completion

November 30, 2024

Last Updated

November 25, 2024

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will not share

Participant data can not be shared due to the GDPR. However, the dataset created can be available upon request from the institution.

Locations