Evaluation of Hereditary Cancer Educational Videos

NCT06157801 | Active Not Recruiting

• 2 other identifiers: 2023-0654NCI-2023-10074
• Study Type: observational
• Target: 43
• Locations: 1 country
• Sites: 1

Brief Summary

To learn if educational videos can help participants be more informed about hereditary cancers (ones that run in the family).

Conditions

Hereditary Cancer

Outcome Measures

Primary Outcomes (1)

• Hereditary Cancer Multidimensional Measure of Informed Choice Questionnaires

  Hereditary Cancer Multidimensional Measure of Informed Choice (MMIC) Knowledge Score scale: (1-8) true or false

  through study completion; an average of 1 year

Study Arms (2)

Interview Study

In the interview study, participants will watch the video, then complete an interview. This will take about 50 minutes.

Behavioral: Interview Study

Survey Study

In the survey study, participants will complete a survey about your education and complete a quick test about your knowledge of hereditary cancer. Participants will then watch the video. complete another survey similar to the one before the video. This should take about 30 minutes.

Behavioral: Survey Study

Interventions

Survey Study BEHAVIORAL

All study participants will have the following demographic information collected from their medical records: * Sex (Male/Female/Other) * Date of birth * Preferred language (English/Spanish) * Health insurance status (for example: private insurance, HCHD "gold card") * Cancer diagnosis (if yes: cancer type/organ, date of pathology diagnosis) * Genetic testing result (gene with pathogenic/likely pathogenic variant) * Date of genetic testing result * Date of documented result disclosure.

Survey Study

Interview Study BEHAVIORAL

All study participants will have the following demographic information collected from their medical records: * Sex (Male/Female/Other) * Date of birth * Preferred language (English/Spanish) * Health insurance status (for example: private insurance, HCHD "gold card") * Cancer diagnosis (if yes: cancer type/organ, date of pathology diagnosis) * Genetic testing result (gene with pathogenic/likely pathogenic variant) * Date of genetic testing result * Date of documented result disclosure.

Interview Study

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The Harris Health System (LBJ Hospital)

You may qualify if:

• Participants of The Harris Health System Lyndon B. Johnson (LBJ) Hospital outpatient oncology clinics (i.e., Gynecologic Oncology, Medical Oncology).
• years of age or older.
• Speaks and/or reads English or Spanish.
• Has a pathogenic or likely pathogenic variant (mutation) in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM on germline genetic testing.
• Has a documented genetic testing results disclosure encounter (i.e. telephone call, follow-up appointment).

You may not qualify if:

• No longer receives outpatient care at LBJ Hospital at time of recruitment.
• Has only a variant of uncertain significance in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM.
• Has only a pathogenic or likely pathogenic variant in gene other than BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, or EPCAM.
• Is unwilling, unable, or requires a legally authorized representative to provide informed consent.

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead

Study Sites (1)

MD Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Links

• MD Anderson Cancer Center

MeSH Terms

Interventions

Longitudinal Studies

Intervention Hierarchy (Ancestors)

Cohort Studies; Epidemiologic Studies; Epidemiologic Study Characteristics; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Jose Rauh-Hain, MD

  M.D. Anderson Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 27, 2023
• First Posted: December 6, 2023
• Study Start: April 5, 2024
• Primary Completion (Estimated): October 31, 2027
• Study Completion (Estimated): October 31, 2027
• Last Updated: March 4, 2026

Record last verified: 2026-03

Locations

US (1)