NCT06156605

Brief Summary

The goal of this clinical trial is to test in the effects of pain pressure threshold (PPT) looking out to 30 minutes in the lumbar spine. The main question\[s\] it aims to answer are: • Is there a difference between PPT from baseline, immediately after, or 30 minutes after compared to sham ultrasound control group? Participants will be exposed to sham ultrasound or sidelying lumbar manipulation with between groups and within group comparisons of PPT at the posterior superior iliac spine up to 30 minutes following the intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
55

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 18, 2023

Completed
10 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 28, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 28, 2023

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 25, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

December 5, 2023

Completed
Last Updated

December 5, 2023

Status Verified

December 1, 2023

Enrollment Period

10 days

First QC Date

November 25, 2023

Last Update Submit

December 4, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain pressure threshold

    PPT at the right PSIS

    Baseline, Immediately after, 30 minutes after

Study Arms (2)

Sidelying lumbar manipulation

EXPERIMENTAL

Right sided lumbar manipulation

Procedure: Sidelying lumbar manipulation

Sham ultrasound

ACTIVE COMPARATOR

Sham (non-therapeutic settings) ultrasound at the right PSIS

Procedure: Sidelying lumbar manipulation

Interventions

R sided lumbar manipulation

Sham ultrasoundSidelying lumbar manipulation

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Asymptomatic individuals between the ages of 18-50

You may not qualify if:

  • Current low back pain (LBP)
  • A history of low back pain LBP within the last three months
  • Previous spinal surgery
  • Rheumatological condition or neurological symptoms or conditions
  • Recent ingestion of pain-relieving medications within the last 24 hours
  • A lumbar manipulation within three days prior to the exam
  • Exhibited any contraindications to manipulation
  • Positive findings during screening precautions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Mary

Bismarck, North Dakota, 58503, United States

Location

Related Publications (1)

  • Schumacher MR, Swanson C, Wolff S, Orteza R, Aguilar R. Exploring the immediate and short-term effect of lumbar spinal manipulation on pressure pain threshold: a randomized controlled trial of healthy participants. Chiropr Man Therap. 2024 May 29;32(1):19. doi: 10.1186/s12998-024-00540-5.

MeSH Terms

Conditions

Spinal InjuriesPain

Condition Hierarchy (Ancestors)

Back InjuriesWounds and InjuriesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Schumacher, PT, DPT, OCS, FAAOMPT

Study Record Dates

First Submitted

November 25, 2023

First Posted

December 5, 2023

Study Start

September 18, 2023

Primary Completion

September 28, 2023

Study Completion

September 28, 2023

Last Updated

December 5, 2023

Record last verified: 2023-12

Data Sharing

IPD Sharing
Will not share

Locations