Coca-Cola Zero (®) Consumption on Night-call Inpatient Course and Mortality

NCT06155981 | Active Not Recruiting

• 1 other identifier: DukeNushssrkyh-01
• Study Type: interventional
• Target: 160
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine the effect of coke zero consumption by night-call staffs on inpatient admission and mortality, and total sleep duration during the night-call duty. Coke Zero is a soft drink that is widely popular within the medical community, carrying the meaning of "zero", which to some, signifies the minimal level of morbidity and mortality that will occupy the on-call the night staffs.

Conditions

Mortality

Keywords

Coke Zero; Night-call Staffs; Inpatient Admission; Inpatient Course; Inpatient Mortality

Outcome Measures

Primary Outcomes (3)

• Inpatient Mortality

  For patients assigned under the designated night-call doctor's care

  The designated night-call doctor's shift from 5PM to 8AM the next day

• Inpatient general ward admission

  For patients assigned under the designated night-call doctor's care

  The designated night-call doctor's shift from 5PM to 8AM the next day

• Inpatient High Dependency/Intensive Care Unit Admission

  For patients assigned under the designated night-call doctor's care

  The designated night-call doctor's shift from 5PM to 8AM the next day

Secondary Outcomes (4)

• Hours of sleep during the night-call

  The designated night-call doctor's shift from 5PM to 8AM the next day

• Hours of shift during the night-call

  The designated night-call doctor's shift from 5PM to 8AM the next day

• Number of steps walked by the night-call staff during the night-call

  The designated night-call doctor's shift from 5PM to 8AM the next day

• Level of alertness of the night-call staff after the night-call

  The designated night-call doctor's shift from 5PM to 8AM the next day

Study Arms (2)

Coke Zero Arm

EXPERIMENTAL

The participant will be given a Coke Zero before each night-call duty for consumption.

Other: Coke Zero

Coke Arm

ACTIVE COMPARATOR

The participant will be given a Coke before each night-call duty for consumption.

Other: Coke

Interventions

Coke Zero OTHER

Coca-Cola Zero Sugar drink will be given.

Coke Zero Arm

Coke OTHER

Coca-Cola drink will be given.

Coke Arm

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Doctors on the night-call roster at Singapore General Hospital

You may not qualify if:

• Other allied health professionals or medical students

Sponsors & Collaborators

• Duke-NUS Graduate Medical School: lead

Study Sites (1)

Singapore General Hospital

Singapore, 169608, Singapore

Location

Related Publications (1)

• Tan MH, Lee Z, Ng B, Sim ES, Chua YY, Tien M, Ooi CJ. The Tao of bao: a randomised controlled trial examining the effect of steamed bun consumption on night-call inpatient course and mortality. Ann Acad Med Singap. 2008 Mar;37(3):255-3.

  PMID: 18392313 BACKGROUND

MeSH Terms

Interventions

Coke

Intervention Hierarchy (Ancestors)

Coal; Fossil Fuels; Complex Mixtures; Energy-Generating Resources; Environment; Environment and Public Health

Study Officials

• Yu Heng Kwan, MD, PhD

  SingHealth Internal Medicine Residency

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Participants will not be aware of the type of drink they receive.
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle Investigator

Model Details: Two groups of night-call staffs will be receiving different interventions.

Study Record Dates

• First Submitted: November 18, 2023
• First Posted: December 5, 2023
• Study Start: January 10, 2024
• Primary Completion: February 2, 2024
• Study Completion: December 31, 2024
• Last Updated: February 20, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share

Locations

SG (1)