Different Positions on the Diffusion and Blockade Effect of Ultrasound-guided Erector Spinae Plane Block

NCT06142630 | Completed

• 1 other identifier: KY20230915-04
• Study Type: interventional
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

After the completion of erector spinae plane block, the patient maintains different positions to assess the diffusion of local anesthetic and the effect of the block.

Conditions

Erector Spinea Plane Block

Outcome Measures

Primary Outcomes (1)

• Incidence and number of local anesthetic diffusion segment into the paravertebral space

  Observation of local anesthetic spread spread into the paravertebral space with CT by a researcher who was blinded to group allocation

  30 minute after completion of the ESPB block

Secondary Outcomes (3)

• Diffusion of local anesthetic into intercostal space

  30 minute after completion of the block

• Diffusion of local anesthetic into the epidural space

  30 minute after completion of the block

• Sensory loss of cold

  30 minute immediately after completion of the nerve block

Study Arms (3)

Supine group

NO INTERVENTION

Patients remained supine

Prone group

EXPERIMENTAL

Patient remained prone

Lateral position group

EXPERIMENTAL

Patient remained in a lateral position

Other: Alteration of patients' position after erector spinae plane block

Interventions

Alteration of patients' position after erector spinae plane block OTHER

After the erector spinae plane block was completed, the patients kept supine, lateral or prone position according to the group allocated for 30 minute to ensure the spread of local anesthetic

Lateral position group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients received CT guided puncture localization of pulmonary nodules under local anesthesia

You may not qualify if:

• Allergic to local anesthetic
• History of opioid abuse
• Severe skin infection
• Peripheral neuropathy
• Dysfunction of blood coagulation

Sponsors & Collaborators

• Nanjing First Hospital, Nanjing Medical University: lead

Study Sites (1)

Nanjing First Hospital

Nanjing, Nanjing, 210006, China

Location

Related Publications (4)

• Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451.

  PMID: 27501016 BACKGROUND

• Munoz F, Cubillos J, Bonilla AJ, Chin KJ. Erector spinae plane block for postoperative analgesia in pediatric oncological thoracic surgery. Can J Anaesth. 2017 Aug;64(8):880-882. doi: 10.1007/s12630-017-0894-0. Epub 2017 Apr 26. No abstract available.

  PMID: 28447318 BACKGROUND

• Ueshima H, Otake H. RETRACTED: Erector spinae plane block provides effective pain management during pneumothorax surgery. J Clin Anesth. 2017 Aug;40:74. doi: 10.1016/j.jclinane.2017.04.016. Epub 2017 Apr 28. No abstract available.

  PMID: 28625453 BACKGROUND

• Shan T, Zhang X, Zhao Z, Zhou X, Bao H, Su C, Tan Q, Han L, Yin J. Spread of local anaesthetic after erector spinae plane block: a randomised, three-dimensional reconstruction, imaging study. Br J Anaesth. 2025 Mar;134(3):830-838. doi: 10.1016/j.bja.2024.10.046. Epub 2025 Jan 8.

  PMID: 39788818 DERIVED

Study Officials

• Gu Jianping

  Nanjing First Hospital, Nanjing Medical University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 26, 2023
• First Posted: November 21, 2023
• Study Start: November 21, 2023
• Primary Completion: March 15, 2024
• Study Completion: December 1, 2024
• Last Updated: February 10, 2025

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)