The Prevalence of the Linburg-Comstock Variation

NCT06142370 | Unknown

• 1 other identifier: RussellSage1
• Study Type: interventional
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to explore the physical exam characteristics of patients referred to orthopedic surgeons with a diagnosis of thumb carpometacarpal (CMC) arthritis. CMC osteoarthritis of the thumb is one of the most common degenerative conditions of the hand in 11% of men and 33% of women (Gillis et al., 2011). Patients with CMC arthritis may experience pain, decreased range of motion, loss of grip and pinch strength, often limiting participation in activities of daily living (Bertozzi et al., 2014). In 1979, two physicians identified a variation of a tendinous connection in the wrist between the tip of the index finger and the tip of the thumb known as the Linburg-Comstock variation (LCV) (Linburg \& Comstock, 1979). The prevalence of the LCV varies respectively from 13-66% in both males and females (Erić et al., 2019). A physical examination of patients with LCV reveals concurrent flexion of the flexor digitorum profundus to the index finger and flexor pollicis longus. The study aims to gain more insight into patients diagnosed with CMC arthritis through clinical examination for LCV to consider an association of the diagnoses. Currently, there is no evidence surrounding patients with symptomatic CMC arthritis and LCV. The hypothesis is that there is an association between symptomatic CMC arthritis and LCV. Patients with a LCV may then be more likely to develop painful CMC arthritis.

Conditions

Anomaly; Hand

Outcome Measures

Primary Outcomes (1)

• LCV

  A positive or negative clinical exam

  10 seconds

Study Arms (1)

Positive LCV

OTHER

A patient who tests positive by clinical exam of a LCV.

Other: Descriptive

Interventions

Descriptive OTHER

The patients will be asked by the recruiting physicians to perform a clinical examination looking for the LCV, which will take a total of five seconds. This is a self-test and not part of a regular clinical examination

Positive LCV

Eligibility Criteria

• Age: 35 Years - 89 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male and female
• Over the age of 35
• Under the age of 89
• Diagnosis of thumb CMC arthritis, ICD-10 code M19.12
• Initial non-surgical intervention for thumb CMC arthritis

You may not qualify if:

• Under the age of 35
• Over the age of 89
• Prisoners

Sponsors & Collaborators

• Russell Sage College: lead
• Albany Medical College: collaborator

Study Sites (1)

The Bone and Joint Center

Albany, New York, 12204, United States

Location

MeSH Terms

Conditions

Hand Deformities

Condition Hierarchy (Ancestors)

Musculoskeletal Diseases

Study Officials

• Chris Mulligan

  Russell Sage College

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: November 16, 2023
• First Posted: November 21, 2023
• Study Start: May 7, 2022
• Primary Completion: May 10, 2024
• Study Completion: May 10, 2025
• Last Updated: November 21, 2023

Record last verified: 2023-11

Locations

US (1)