Comparison of Follicle Diameter on hCG Day and Follicle Diameters on OPU (Oocyte Pick up) Day and the Effect of Follicle Diameters on Embryo Development and Pregnancy Outcomes

NCT04679688 | Unknown

• 1 other identifier: ATAKIVF
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 2

Brief Summary

Evaluation of follicle diameters on human chorionic gonadotrophin(hCG) day and oocyte pick up (OPU) day of follicles developing after gonadotropin treatment, the relationship between follicle diameter and maturation in oocytes obtained after OPU and its effect on pregnancy outcomes will be investigated. In order to make it easier to measure and enumerate the follicle diameters with the help of vaginal ultrasound, patients under 35 years of age with at most five follicles in any ovary and at least four follicles in both ovaries will be included in the study.

Conditions

HCG Day Follicle Diameter, Reproduction Results

Outcome Measures

Primary Outcomes (2)

• Live birth rate

  live birth rate of participants

  15 months

• Clinical pregnancy rate

  clinical pregnancy rate of participants

  6 months

Secondary Outcomes (1)

• Oocyte maturation

  6 months

Interventions

descriptive OTHER

Those who apply for IVF treatment and have an antral follicle number of 4-10 will be included in the treatment. The reason for including patients with this number of antral follicles in the study is to determine the follicle locations and to determine each growing follicle separately on the day of hCG and egg collection.

Also known as: The effect of follicle diameters on embryo development and pregnancy outcomes.

Eligibility Criteria

• Age: 23 Years - 40 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patient group with at least 5 and at most 10 follicles in each ovary whose hCG day exceeds 11 mm,
• Patient group with BMI below 30.

You may not qualify if:

• PCO patient group,
• Male factor group with severe OAT,
• Patient group with endometriosis,
• Patient group with PGD indication,
• The group under the age of 40 and legally deserving of double embryo transfer

Sponsors & Collaborators

• Acibadem University: lead

Study Sites (2)

Acıbadem University Atakent Hospital

Istanbul, Küçükçekmece, 34303, Turkey (Türkiye)

RECRUITING

Acibadem MAA University Atakent Hospital

Istanbul, 34457, Turkey (Türkiye)

ACTIVE NOT RECRUITING

MeSH Terms

Interventions

Pregnancy Outcome

Intervention Hierarchy (Ancestors)

Prognosis; Diagnosis; Pregnancy; Reproduction; Reproductive Physiological Phenomena; Reproductive and Urinary Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 17, 2020
• First Posted: December 22, 2020
• Study Start: December 20, 2020
• Primary Completion: August 20, 2021
• Study Completion: December 20, 2021
• Last Updated: January 6, 2021

Record last verified: 2020-12

Locations

TU (2)