Vitamin D Supplementation in Acne
Vitamin D Supplementation in Combination With Azithromycin and Topical Retinoid for Acne: A Randomized Controlled Trial
1 other identifier
interventional
58
1 country
1
Brief Summary
The goal of this clinical trial is to compare in acne vulgaris patients. The main question it aims to answer is: • To assess the therapeutic benefit of vitamin D supplement in acne vulgaris treatment, following a 2-month treatment regimen that includes vitamin D supplementation compared to conventional (systemic azithromycin and topical retinoid) treatment alone. Participants will receive vitamin D supplements in addition to capsule Azithromycin and topical retinoid. Researchers will compare groups to determine efficacy of Vitamin D supplements in the treatment of Acne vulgaris.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Feb 2024
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 23, 2023
CompletedFirst Posted
Study publicly available on registry
November 21, 2023
CompletedStudy Start
First participant enrolled
February 24, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2024
CompletedAugust 29, 2024
August 1, 2024
6 months
October 23, 2023
August 27, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Efficacious
Improvement in Global Acne Grading System Score from baseline to after 2 months of treatment
2 months
Study Arms (2)
Vitamin D
EXPERIMENTALPlacebo
ACTIVE COMPARATORInterventions
Eligibility Criteria
You may qualify if:
- Individuals aged between 13 and 40 years with diagnoses of Acne vulgaris are included.
You may not qualify if:
- Individuals currently undergoing treatment for polycystic ovary syndrome (PCOs)
- Those with obesity
- Individuals employing vitamin supplementation
- Those under the influence of topical or systemic steroids and acne treatment in the last 2 months.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hitec-Ims
Islamabad, Punjab Province, 47080, Pakistan
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor, MBBS, FCPS
Study Record Dates
First Submitted
October 23, 2023
First Posted
November 21, 2023
Study Start
February 24, 2024
Primary Completion
September 1, 2024
Study Completion
October 1, 2024
Last Updated
August 29, 2024
Record last verified: 2024-08
Data Sharing
- IPD Sharing
- Will not share
not sharing