Correlation Between Acne Vulgaris and Lipid Profile Among Young Adults in Sohag Governorate

NCT07062081 | Not Yet Recruiting

• 1 other identifier: Soh-Med-25-06-18MS
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Acne vulgaris is the most common skin condition affecting late adolescents worldwide.1 The prevalence of acne is said to be 85% in adults aged 12 to 25 years.2 Almost all teenagers between 15 and 17 years report having some degree of acne.3 Estimates of the lifetime occurrence of acne in the literature range from 0.1%4 to as high as 85.1%5 in the general population, depending on the age range, region, and method of sampling. Overall, acne is more common in women,8,9 but in some literature the prevalence is approximately equal in men and women.10,11

Conditions

Acne Vulgaris

Outcome Measures

Primary Outcomes (3)

• lipid profile (TG)

  The blood samples were taken to measure lipid profile levels as triglycerides (TG)

  6 months

• lipid profile (HDL)

  The blood samples were taken to measure lipid profile levels as HDL

  6 months

• lipid profile (VLDL)

  The blood samples were taken to measure lipid profile levels as VLDL

  6 months

Interventions

lipid profile DIAGNOSTIC_TEST

The blood samples were taken to measure lipid profile levels as triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL), and high-density lipoprotein cholesterol (HDL) and VLDL values.

Eligibility Criteria

• Age: 12 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• age- and sex-matched healthy volunteers, not taking any medicine, and having no personal or family history of acne.

You may not qualify if:

• : reluctance to take part in the study, pregnancy or lactation
• intake of oral contraception or hormone therapy, history of taking any medications that affect lipid metabolism or oral isotretinoin
• and systemic diseases that affect the metabolism of lipids, such as uncontrolled diabetes, hypothyroidism, nephrotic syndrome, end-stage renal failure, HIV, familial hypercholesterolemia, and metabolic syndrome.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag university Hospital

Sohag, Egypt

Location

Related Publications (4)

• Degitz K, Ochsendorf F. Pharmacotherapy of acne. Expert Opin Pharmacother. 2008 Apr;9(6):955-71. doi: 10.1517/14656566.9.6.955.

  PMID: 18377339 BACKGROUND

• Gibbs S. Skin disease and socioeconomic conditions in rural Africa: Tanzania. Int J Dermatol. 1996 Sep;35(9):633-9. doi: 10.1111/j.1365-4362.1996.tb03687.x.

  PMID: 8876289 BACKGROUND

• Dreno B. Treatment of adult female acne: a new challenge. J Eur Acad Dermatol Venereol. 2015 Jun;29 Suppl 5:14-9. doi: 10.1111/jdv.13188.

  PMID: 26059821 BACKGROUND

• Collier CN, Harper JC, Cafardi JA, Cantrell WC, Wang W, Foster KW, Elewski BE. The prevalence of acne in adults 20 years and older. J Am Acad Dermatol. 2008 Jan;58(1):56-9. doi: 10.1016/j.jaad.2007.06.045. Epub 2007 Oct 22.

  PMID: 17945383 BACKGROUND

MeSH Terms

Conditions

Acne Vulgaris

Condition Hierarchy (Ancestors)

Acneiform Eruptions; Skin Diseases; Skin and Connective Tissue Diseases; Sebaceous Gland Diseases

Central Study Contacts

Hager A dardier, demonastrator

CONTACT

01129977680; hager.dardir@med.sohag.edu.eg

hanan A metwaly, professor

CONTACT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: demonostrator at family medicine department

Study Record Dates

• First Submitted: July 2, 2025
• First Posted: July 14, 2025
• Study Start: August 1, 2025
• Primary Completion: January 30, 2026
• Study Completion: January 30, 2026
• Last Updated: July 14, 2025

Record last verified: 2025-07

Locations

EG (1)